Results 41 to 50 of about 24,508,395 (287)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ESTUDIO DEL INGRESO DE HIDRÓGENO EN ACERO ELECTROCINCADO MEDIANTE ANÁLISIS TÉRMICO

open access: yesAvances en Ciencias e Ingeniería, 2020
The aim of this work is to study the hydrogen input in SAE 1005 steel wire samples during the successive stages of the electrolytic galvanizing process.
María N. Delpupo   +3 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Thermal Elastohydrodynamic Lubrication Analysis of Automotive Differential Bevel Gear Under Differential Condition

open access: yesJixie chuandong, 2019
In order to study the meshing thermal characteristics of the differential bevel gear under differential conditions, based on the thermal elastohydrodynamic lubrication theory, an unsteady thermal elastohydrodynamic lubrication model of straight bevel ...
Cong Wei   +3 more
doaj  

comparative isothermal and differential thermal analysis of epoxy-polyurea / metal blends alloys [PDF]

open access: yesمجلة التربية والعلم, 2008
In this work, comparative isothermal and differential thermal analysis of epoxy-polyurea / metal blends were investigated. IGA measurements show fast loss in weight in the first 20 minutes before they reached a constant weight, while the period where ...
Akram Mohammed, Mahmoud Hasen
doaj   +1 more source

Cure kinetics of liquid crystalline epoxy resins based on biphenyl mesogen [PDF]

open access: yes, 2014
The cure kinetics of a biphenyl-based liquid crystalline (LC) epoxy resin (LCER) was studied using differential scanning calorimetry (DSC) and polarized optical microscopy. The effects of LC phase formation on the cure kinetics were investigated.
Kessler, Michael, Li, Yuzhan
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The investigation of quality of power-transistor crystals soldering by a transient impedance-spectrometer [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2012
Differential distribution profiles of the thermal «junction-to-case» resistance of KP723G transistors in accordance with the attachment of the crystals into the package have been investigated.
Turtsevich А. S.   +6 more
doaj   +2 more sources

Effect of Nano-TiO2 Dioxide on the Hydration Process of Tunnel Construction in Low-Temperature Environments

open access: yesNanomaterials
To address winter construction challenges such as slow early-stage strength development, inhibited hydration processes, and pore structure defects in concrete under low-temperature conditions, this study employs nano-TiO2 as a modifying agent.
Yongchun Jiao   +5 more
doaj   +1 more source

Developing thermal insulation cement-based mortars with recycled aggregate in accordance with net zero principles [PDF]

open access: yesScience of Sintering
The performance of thermo-insulation rendering mortars with alternations in ratios of powdered cordierite and talc was examined. The goal was to confirm that recycled kilnware cordierite can be reapplied in the mortar design without significant ...
Pavlović Marko   +3 more
doaj   +1 more source

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