Results 1 to 10 of about 1,609,951 (243)

Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer

BMC Cancer, 2021
This study aimed to explore and identify key genes and signaling pathways that contribute to the progression of cervical cancer to improve prognosis. Three gene expression profiles (GSE63514, GSE64217 and GSE138080) were screened and downloaded from the ...
Baojie Wu, Shuyi Xi
semanticscholar   +1 more source

Lactate metabolism-related differentially expressed genes reveal biological mechanisms underlying sarcopenia. [PDF]

Sci Rep
Li Y, Xu Z.
europepmc   +2 more sources

Potential biomarkers and molecular mechanisms in preeclampsia progression

Open Life Sciences, 2022
This study aimed to explore potential biomarkers and molecular mechanisms in preeclampsia (PE) progression. Gene expression profiles of GSE147776 and GSE96984 were downloaded, followed by the identification of common differentially expressed genes (co ...
Li Guohua, Huang Shijia, Liu Xiaosong, Du Qiaoling   +3 more
doaj   +1 more source

12 Survival-related differentially expressed genes based on the TARGET-osteosarcoma database

Experimental biology and medicine, 2021
The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) project aims to determine molecular changes that drive childhood cancers, including osteosarcoma.
Emel Rothzerg, Jiake Xu, D. Wood, S. Kõks   +3 more
semanticscholar   +1 more source

Identification of the transcriptome profile of after mebendazole treatment [PDF]

Kosin Medical Journal, 2022
Background The scuticociliate Miamiensis avidus is a major pathogenic agent that causes significant economic losses in the flounder aquaculture industry. Many different types of drugs are being tested to control this disease, including mebendazole, which
Hyunsu Kim, A-Reum Lee, Kyung-Yoon Jeon, Eun-Ji Ko, Hee-Jae Cha, Mee Sun Ock   +5 more
doaj   +1 more source

What genes are differentially expressed in individuals with schizophrenia? A systematic review

Molecular Psychiatry, 2022
Schizophrenia is a severe, complex mental disorder characterized by a combination of positive symptoms, negative symptoms, and impaired cognitive function.
Alison K. Merikangas, Matthew J Shelly, Alexys R. Knighton, Nicholas Kotler, N. Tanenbaum, L. Almasy   +5 more
semanticscholar   +1 more source

Uncovering potential genes in colorectal cancer based on integrated and DNA methylation analysis in the gene expression omnibus database

BMC Cancer, 2022
Background Colorectal cancer (CRC) is major cancer-related death. The aim of this study was to identify differentially expressed and differentially methylated genes, contributing to explore the molecular mechanism of CRC.
Guanglin Wang, Feifei Wang, Zesong Meng, Na Wang, Chaoxi Zhou, Juan Zhang, Lianmei Zhao, Guiying Wang, Baoen Shan   +8 more
doaj   +1 more source

A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data

Nature Communications, 2020
A common analysis of single-cell sequencing data includes clustering of cells and identifying differentially expressed genes (DEGs). How cell clusters are defined has important consequences for downstream analyses and the interpretation of results, but ...
A. Vandenbon, Diego Diez
semanticscholar   +1 more source

Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach

Frontiers in Genetics, 2020
Background and Aims: Familial hypercholesterolemia (FH) is one of the major risk factor for the progression of atherosclerosis and coronary artery disease.
S. Udhaya Kumar, D. Thirumal Kumar, R. Bithia, Srivarshini Sankar, R. Magesh, Mariem Sidenna, C. George Priya Doss, H. Zayed   +7 more
semanticscholar   +1 more source

Transcriptomic and proteomic analyses of ovarian follicles reveal the role of VLDLR in chicken follicle selection

BMC Genomics, 2020
Background Follicle selection in chickens refers to the process of selecting one follicle from a group of small yellow follicles (SY, 6–8 mm in diameter) for development into 12–15 mm hierarchical follicles (usually F6 follicles), which is an important ...
Qiuyue Chen, Yiya Wang, Zemin Liu, Xiaoli Guo, Yi Sun, Li Kang, Yunliang Jiang   +6 more
doaj   +1 more source