Results 91 to 100 of about 1,609,951 (243)
The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing
Journal of Hematology & Oncology, 2020 Pediatric myelodysplastic syndrome (PMDS) is a very rare and still poorly characterized disorder. In this work, we identified novel potential targets of PMDS by determining genes with aberrant expression, which can be correlated with PMDS pathogenesis ...
Lorena Zubovic +16 more
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New differentially expressed genes and differential DNA methylation underlying refractory epilepsy
OncoTarget, 2016 Epigenetics underlying refractory epilepsy is poorly understood, especially in patients without distinctive genetic alterations. DNA methylation may affect gene expression in epilepsy without affecting DNA sequences.
Xi Liu +10 more
semanticscholar +1 more source
Cancer outlier differential gene expression detection [PDF]
Biostatistics, 2006 We study statistical methods to detect cancer genes that are over- or down-expressed in some but not all samples in a disease group. This has proven useful in cancer studies where oncogenes are activated only in a small subset of samples. We propose the outlier robust t-statistic (ORT), which is intuitively motivated from the t-statistic, the most ...
openaire +2 more sources
Translational Psychiatry, 2017 We undertook an RNA sequencing (RNAseq)-based transcriptomic profiling study on lymphoblastoid cell lines of a European ancestry sample of 529 schizophrenia cases and 660 controls, and found 1058 genes to be differentially expressed by affection status ...
A. Sanders +9 more
semanticscholar +1 more source
Gene expression and differentiation
Current Opinion in Genetics & Development, 1992 T, Maniatis, H, Weintraub
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Differentially Expressed Genes in EEC and LMS Syndromes.
PLoS ONE, 2015 ObjectivesEctrodactyly ectodermal dysplasia cleft lip/palate (EEC) syndrome and limb-mammary syndrome (LMS) share a similar phenotype and the same pathogenic gene, which complicates the ability to distinguish between these diagnoses.
Wei Yin +3 more
doaj +1 more source
What is a Differentially Expressed Gene?
bioRxivThe concept of ‘Differentially Expressed Genes’ (DEGs) is central to RNA-Seq studies, yet their identification suffers from reproducibility issues. This is largely a consequence of the inherent biological and technical variation that cannot be captured ...
Franziska Hoerbst +3 more
semanticscholar +1 more source
PLoS ONE, 2015 To explore the patterns of gene expression in gastric cancer, a total of 26 paired gastric cancer and noncancerous tissues from patients were enrolled for gene expression microarray analyses. Limma methods were applied to analyze the data, and genes were
Hao Li +8 more
semanticscholar +1 more source
Cancer Management and Research, 2022 Hengyu Tian, Yuanyuan Chen, Renjie Zhang, Jialin Liu Department of Hepatobiliary Surgery, Shenzhen Traditional Chinese Medicine Hospital/The fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, 518033, People ...
Tian H, Chen Y, Zhang R, Liu J
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