Results 81 to 90 of about 3,651,834 (302)

Identification of differentially expressed immune-relevant genes in Chinese soft-shelled turtle (Trionyx sinensis) infected with Aeromonas hydrophila

, 2008
Expressed sequence tag (EST) analysis is an efficient tool for gene discovery and profiling gene expression. Aeromonas hydrophila, a ubiquitous waterborne bacterium, is one of the most frequent pathogens isolated from diseased aquatic organisms. In order
Guo, Qionglin, Guo, QL, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China, Zhou, Xiuxia, Dai, Heping   +3 more
core   +1 more source

RNA-seq analysis-based study on the effects of gestational diabetes mellitus on macrosomia

Frontiers in Endocrinology
BackgroundBoth the mother and the infant are negatively impacted by macrosomia. Macrosomia is three times as common in hyperglycemic mothers as in normal mothers.
Qianqian Gao, Qianqian Gao, Qianqian Gao, Guanying Xu, Guijie Wang, Wei Wang, Chao Zhu, Chao Zhu, Chao Zhu, Yang Shi, Changzhuang Guo, Jing Cong, Hongxia Ming, Dongmei Su, Dongmei Su, Xu Ma, Xu Ma   +16 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Differentially expressed genes (DEGs).

, 2021
(A) Numbers of differentially expressed genes between given treatments and the control (H2O). (B) Venn diagram showing alleviation-related gene numbers in each alleviation treatment.
Xiaoxin Wang (586774), Tong Sun (1564231), Gen Fang (552940), Jing Yang (13969), Yangsheng Li (552942)   +4 more
core   +1 more source

Evaluation of Combining Several Statistical Methods with a Flexible Cutoff for Identifying Differentially Expressed Genes in Pairwise Comparison of EST Sets

Bioinformatics and Biology Insights, 2008
The detection of differentially expressed genes from EST data is of importance for the discovery of potential biological or pharmaceutical targets, especially when studying biological processes in less characterized organisms and where large-scale ...
Angelica Lindlöf, Marcus Bräutigam, Aakash Chawade, Olof Olsson, Björn Olsson   +4 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Differential Gene Expression in Pseudoexfoliation Syndrome

Investigative Opthalmology & Visual Science, 2005
To identify and characterize genes differentially expressed in anterior segment tissues of eyes with pseudoexfoliation (PEX) syndrome and glaucoma.Anterior segment tissues (iris, ciliary processes, lens epithelium) were obtained from eight surgically enucleated eyes with PEX-associated open-angle or closed-angle glaucomas and eight age-matched ...
Zenkel, Matthias, Pöschl, Ernst, von der Mark, Klaus, Hofmann-Rummelt, Carmen, Naumann, Gottfried O. H., Kruse, Friedrich E., Schlotzer-Schredhardt, Ursula   +6 more
openaire   +3 more sources

Significant differentially expressed genes.

, 2023
Gene types that were significant differentially expressed in Stage 1 (A) and Stage 2 (B) r-HAT. Protein coding genes were the most differential expressed followed by lcnRNA and pseudogenes in both stage 1 and 2 r-HAT. (TIF)
Oscar Nyangiri (11134007), Annette MacLeod (12779), Enock Matovu (150725), Janelisa Musaya (7024463), Harry Noyes (121595), Peter Nambala (7245215), Joyce Namulondo (6954626), Barbara Nerima (370317), Vincent Pius Alibu (4875841), Julius Mulindwa (252110)   +9 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Analysis of differentially expressed genes in response to endogenous cytokinins during cotton leaf senescence

, 2013
Cytokinins have been implicated in delaying leaf senescence. We previously generated transgenic cotton (Gossypium hirsutum L.) plants that harbor the Agrobacterium isopentenyl transferase gene (ipt) directed by a proteinase gene promoter. Here, we report
P. Zhao, Y. D. Liu, Z. J. Yin, N. Zhang, F. F. Shen   +4 more
core   +1 more source