Results 61 to 70 of about 678,844 (309)

Identification of potential hub genes involved in alcohol use disorder via bioinformatics analysis

Sichuan jingshen weisheng, 2023
BackgroundAlcohol use disorder （AUD） is a type of chronic relapsing brain disorder. Genetic factors play an important role in the pathogenesis of AUD.
Zhao Rong, Zhu Youwei, Xie Bin
doaj   +1 more source

Differential placental gene expression in preeclampsia [PDF]

The FASEB Journal, 2008
Objective: Candidate genes associated with preeclampsia have not been fully described. We conducted a microarray study to investigate global placental gene expression in preeclampsia. Study design: Cases (n=18) and controls (n=18) were selected among patients receiving care at Swedish Medical Center, Seattle, WA.
Daniel A, Enquobahrie, Margaret, Meller, Kenneth, Rice, Bruce M, Psaty, David S, Siscovick, Michelle A, Williams   +5 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Differentially expressed genes (DEGs).

, 2021
(A) Numbers of differentially expressed genes between given treatments and the control (H2O). (B) Venn diagram showing alleviation-related gene numbers in each alleviation treatment.
Xiaoxin Wang (586774), Tong Sun (1564231), Gen Fang (552940), Jing Yang (13969), Yangsheng Li (552942)   +4 more
core   +1 more source

Identification of MicroRNA-Target Gene-Transcription Factor Regulatory Networks in Colorectal Adenoma Using Microarray Expression Data

Frontiers in Genetics, 2020
ObjectiveThe aim of the study was to find the key genes, microRNAs (miRNAs) and transcription factors (TFs) and construct miRNA-target gene-TF regulatory networks to investigate the underlying molecular mechanism in colorectal adenoma (CRA).MethodsFour ...
Yadong Gao, Yadong Gao, Shenglai Zhang, Shenglai Zhang, Yan Zhang, Yan Zhang, Junbo Qian, Junbo Qian   +7 more
doaj   +1 more source

Identification of Key Biomarkers and Pathways for Maintaining Cognitively Normal Brain Aging Based on Integrated Bioinformatics Analysis

Frontiers in Aging Neuroscience, 2022
BackgroundGiven the arrival of the aging population has caused a series of social and economic problems, we aimed to explore the key genes underlying cognitively normal brain aging and its potential molecular mechanisms.MethodsGSE11882 was downloaded ...
Jinling Xu, Jinling Xu, Hui Zhou, Guangda Xiang, Guangda Xiang   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Identification of differentially expressed immune-relevant genes in Chinese soft-shelled turtle (Trionyx sinensis) infected with Aeromonas hydrophila

, 2008
Expressed sequence tag (EST) analysis is an efficient tool for gene discovery and profiling gene expression. Aeromonas hydrophila, a ubiquitous waterborne bacterium, is one of the most frequent pathogens isolated from diseased aquatic organisms. In order
Guo, Qionglin, Guo, QL, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China, Zhou, Xiuxia, Dai, Heping   +3 more
core   +1 more source

Differential Expression of Myrosinase Gene Families [PDF]

Plant Physiology, 1993
In mature seeds of Brassica napus three major and three minor myrosinase isoenzymes were identified earlier. These myrosinases are known to be encoded by at least two different families of myrosinase genes, denoted MA and MB. In the work described in this paper the presence of different myrosinase isoenzymes in embryos, seedlings, and vegetative mature
M, Lenman, A, Falk, J, Rödin, A S, Höglund, B, Ek, L, Rask   +5 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source