Results 21 to 30 of about 1,609,951 (243)
Specific Differentially Methylated and Expressed Genes in People with Longevity Family History
Iranian Journal of Public Health, 2020 Background: We attempt to identify specific differentially methylated and expressed genes in people with longevity family history, it will contribute to discover significant features about human longevity.
Chunhong LI +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Despite the great increase in human lifespan with improved medical care, the physiological and pathological changes such as memory and cognitive disorders and associated anxiety and depression are major concern with aging. Molecular mechanisms underlying
Mengqi Li +10 more
semanticscholar +1 more source
Differential gene expression in mesothelioma [PDF]
FEBS Letters, 2000 To investigate the molecular events controlling malignant transformation of human pleural cells, we compared constitutive gene expression of mesothelioma cells to that of pleural cells. Using cDNA microarray and high‐density filter array, we assessed expression levels of >6500 genes.
Rihn, B.H. +7 more
openaire +2 more sources
Frontiers in Genetics, 2022 Purpose: Recurrent implantation failure (RIF) is an enormous challenge for in vitro fertilization (IVF) clinicians. An understanding of the molecular mechanisms of RIF helps to predict prognosis and develop new therapeutic strategies.
Jin Shang +9 more
doaj +1 more source
RAD: a web application to identify region associated differentially expressed genes
bioRxiv, 2020 With the advance of genomic sequencing techniques, chromatin accessible regions, transcription factor binding sites and epigenetic modifications can be identified at genome-wide scale.
Yixin Guo +5 more
semanticscholar +1 more source
Informatics in Medicine Unlocked, 2021 Gastric cancer (GC) is the third cause of cancer mortality in the world but the molecular mechanisms underlying the pathogenesis of GC remain little known.
Homa Akhavan +3 more
doaj +1 more source
Identification of Key Genes Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma by Bioinformatics Analysis [PDF]
Advanced Ultrasound in Diagnosis and Therapy, 2020 Objective: To explore differentially expressed genes (DEGs) between lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC).Methods: Based on GEO database, we used R software to identify the DEGs and conducted the bioinformatics analysis to ...
Jinru Xue, MS, Yu Yang, MS, Bo Jiang, MD, Linxue Qian, MD, Xian-Quan Shi, PhD
doaj +1 more source
Data-driven detection of subtype-specific differentially expressed genes
Scientific Reports, 2021 Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and
Lulu Chen +7 more
doaj +1 more source
Bayesian Modeling of Differential Gene Expression [PDF]
Biometrics, 2005 Summary We present a Bayesian hierarchical model for detecting differentially expressing genes that includes simultaneous estimation of array effects, and show how to use the output for choosing lists of genes for further investigation. We give empirical evidence that expression‐level dependent array effects are needed, and explore different nonlinear ...
Lewin, Alex +4 more
openaire +2 more sources
Pomelo II: finding differentially expressed genes [PDF]
Nucleic Acids Research, 2009 Pomelo II (http://pomelo2.bioinfo.cnio.es) is an open-source, web-based, freely available tool for the analysis of gene (and protein) expression and tissue array data. Pomelo II implements: permutation-based tests for class comparisons (t-test, ANOVA) and regression; survival analysis using Cox model; contingency table analysis with Fisher's exact test;
Morrissey, Edward R. +1 more
openaire +3 more sources