Results 251 to 260 of about 4,395,934 (279)

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

The Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli, Kavya Phadke, Alessandro Cospito, Xianming Lin, Marina Cerrone, Joanna Abi Rizk, Michael Cammer, Yan Deng, Joseph Sall, Mingliang Zhang, Feng‐Xia Liang, Irene de Lázaro, Mario Delmar   +12 more
wiley   +1 more source

MultiDMPcaller: a one-stop software for detection and visualization of differentially methylated positions and regions. [PDF]

Bioinformatics
Yuan Q, Zhao H, Zhang Z, Yue C, Zhang B, Xue S, Zou Q, Yu J.   +7 more
europepmc   +1 more source

Integrated Methylome and Transcriptome Analyses Reveal Methylation-Associated Cadmium Stress Responses in <i>Sophora tonkinensis</i>. [PDF]

Plants (Basel)
Wei F, Qin S, Lin Y, Li L, Wei G, Tang D, Tang M, Liang Y.   +7 more
europepmc   +1 more source

Mitoepigenetic Alterations in Early-Onset Parkinson's Disease. [PDF]

Int J Mol Sci
Abu Manneh R, Chairta PP, Loizidou MA, Zanti M, Georgiou AN, Michailidou K, Demetriou C, Pantzaris M, Zamba-Papanicolaou E, Hadjisavvas A.   +9 more
europepmc   +1 more source

Haplotype-resolved DNA methylation at the <i>APOE</i> locus identifies allele-specific epigenetic signatures relevant to Alzheimer's disease risk. [PDF]

NPJ Dement
Genner RM, Meredith M, Daida K, Moller A, Weller C, Ayuketah A, Jerez PA, Akeson S, Malik L, Baker B, Kouam C, Paquette K, Catching A, Bromberek S, Hu F, Reed X, Marenco S, Auluck P, Mandal A, Paten B, Gibbs JR, Jain M, Cookson MR, Singleton AB, Nalls M, Blauwendraat C, Billingsley KJ.   +26 more
europepmc   +1 more source

Pattools‑implemented methylation vector analysis reveals aberrant subtype‑specific methylation in lung cancer across tissue and plasma cfDNA. [PDF]

Clin Transl Med
Dong Z, Luo Y, Hu T, Cheng Y, Ren Q, Xu L, Tan Y, Li W, Sun Y, Chen M, Shen Z, Zhang B, Bai Y, Tao Y, Cao Z, Sun D.   +15 more
europepmc   +1 more source

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Beckwith–Wiedemann syndrome with placental chorangioma due to H19‐differentially methylated region hypermethylation: A case report

Journal of Obstetrics and Gynaecology Research, 2011

exaly   +2 more sources

Effects of parental environmental copper stress on offspring development: DNA methylation modification and responses of differentially methylated region-related genes in transcriptional expression.

Journal of Hazardous Materials, 2021
Parental environmental copper (Cu) exposure is widespread, causing problems for sustainability of fish populations, and epigenetics is suggested to be fundamental during the process, but the mechanism is scarcely reported.
Zhi-Peng Tai, Pengpeng Guan, Ting Zhang, Wenye Liu, LingYa Li, You Wu, Guoliang Li, Jing-Xia Liu   +7 more
semanticscholar   +1 more source

Differentially Methylated Region-Representational Difference Analysis (DMR-RDA): A Powerful Method to Identify DMRs in Uncharacterized Genomes.

Methods in molecular biology, 2017
P. Sasheva, U. Grossniklaus
semanticscholar   +1 more source

Vitrification at Day3 stage appears not to affect the methylation status of H19/IGF2 differentially methylated region of in vitro produced human blastocysts.

Cryobiology, 2016
M. Derakhshan-Horeh, F. Abolhassani, F. Jafarpour, A. Moini, K. Karbalaie, S. Hosseini, M. Nasr-Esfahani   +6 more
semanticscholar   +1 more source