Results 41 to 50 of about 4,224,202 (187)
Nature Communications, 2018 Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Guoliang Lyu +10 more
doaj +1 more source
Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression
Scientific Reports, 2023 Liver fibrosis is caused by chronic hepatic injury and may lead to cirrhosis, and even hepatocellular carcinoma. When hepatic stellate cells (HSCs) are activated by liver injury, they transdifferentiate into myofibroblasts, which secrete extracellular ...
Bingyu Ye +8 more
doaj +1 more source
HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. [PDF]
, 2019 Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation.
Chen, Yifang +8 more
core +1 more source
Transactions of the American Mathematical Society, 1995 We deal here with homogeneous polynomials in many variables and their hypercube representation, introduced in [5]. Associated with this representation there is a norm (Bombieri’s norm) and a scalar product. We investigate differential identities connected with this scalar product. As a corollary, we obtain Bombieri’s inequality (originally proved in [4]
Beauzamy, Bernard, Dégot, Jérome
openaire +1 more source
Frontiers in Cellular Neuroscience, 2019 Acquisition of proper neuronal identity and position is critical for the formation of neural circuits. In the embryonic spinal cord, cardinal populations of interneurons diversify into specialized subsets and migrate to defined locations within the ...
Audrey Harris +8 more
doaj +1 more source
Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation
FEBS Open Bio, 2020 Myogenesis is a physiological process which involves the proliferation of myoblasts and their differentiation into multinucleated myotubes, which constitute the future muscle fibers.
Caroline Vergé +5 more
doaj +1 more source
Molecules, 2022 Puerarin (PUR) and gastrodin (GAS) are often used in combined way for treating diseases caused by microcirculation disorders. The current study aimed to investigate the absorption and transportation mechanism of PUR and GAS and their interaction via Caco-
Li Jiang +9 more
doaj +1 more source
Not all job demands are equal: differentiating job hindrances and job challenges in the Job Demands-Resources model [PDF]
, 2010 This study aimed to integrate the differentiation between two types of job demands, as made in previous studies, in the Job-Demands Resources (JD-R) model.
De Witte, Hans +3 more
core +1 more source
Nature Communications, 2017 Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly ...
Ning Huang +7 more
doaj +1 more source
eLife, 2016 Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear.
Kenji Kamimoto +5 more
doaj +1 more source