Results 41 to 50 of about 4,638,915 (335)

Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression

Scientific Reports, 2023
Liver fibrosis is caused by chronic hepatic injury and may lead to cirrhosis, and even hepatocellular carcinoma. When hepatic stellate cells (HSCs) are activated by liver injury, they transdifferentiate into myofibroblasts, which secrete extracellular ...
Bingyu Ye, Mengli Yu, Meijuan Yue, Man Yin, Chunyan Zhang, Qiwen Wang, Xinru Ding, Wenlong Shen, Zhihu Zhao   +8 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Geometric control of myogenic cell fate. [PDF]

, 2006
This work combines expertise in stem cell biology and bioengineering to define the system for geometric control of proliferation and differentiation of myogenic progenitor cells.
Conboy IM, Disatnik MH, Elena M de Juan-Pardo, Irina M Conboy, Massague J, Mike Bao-Trong Hoang, Miller KJ, Partridge TA, Seale P, Tidball JG   +9 more
core   +3 more sources

TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

Nature Communications, 2018
Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Guoliang Lyu, Yiting Guan, Chao Zhang, Le Zong, Lei Sun, Xiaoke Huang, Li Huang, Lijun Zhang, Xiao-Li Tian, Zhongjun Zhou, Wei Tao   +10 more
doaj   +1 more source

Differential identities [PDF]

Transactions of the American Mathematical Society, 1995
We deal here with homogeneous polynomials in many variables and their hypercube representation, introduced in [5]. Associated with this representation there is a norm (Bombieri’s norm) and a scalar product. We investigate differential identities connected with this scalar product. As a corollary, we obtain Bombieri’s inequality (originally proved in [4]
Beauzamy, Bernard, Dégot, Jérome
openaire   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]

, 2015
We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana, Horvai, Andrew E, McCalmont, Timothy H   +2 more
core   +4 more sources

Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

eLife, 2016
Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear.
Kenji Kamimoto, Kota Kaneko, Cindy Yuet-Yin Kok, Hajime Okada, Atsushi Miyajima, Tohru Itoh   +5 more
doaj   +1 more source

Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation

FEBS Open Bio, 2020
Myogenesis is a physiological process which involves the proliferation of myoblasts and their differentiation into multinucleated myotubes, which constitute the future muscle fibers.
Caroline Vergé, Amel Bouchatal, Frédéric Chirat, Yann Guérardel, Abderrahman Maftah, Jean‐Michel Petit   +5 more
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source