Results 111 to 120 of about 3,801,891 (296)

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

C2absorption-line diagnostics of diffuse interstellar clouds [PDF]

, 2017
The excitation of the diatomic carbon molecule in diffuse interstellar clouds is discussed for a cloud with large density fluctuations of small linear filling factor along the line of sight. Possible implications for the chemistry of the diffuse cloud in
Dalgarno, Alexander, Cecchi-Pestellini, Cesare   +1 more
core   +1 more source

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Comparative chemistry of diffuse clouds

, 2001
Using the Plateau de Bure interferometer, we observed the λ3 mm absorption lines of CN, HCN and HNC from some of the diffuse clouds which lie toward our well-studied sample of compact extragalactic mm-wave continuum sources.
R. Lucas, H. Liszt, H. S. Liszt
core   +1 more source

Formation and Evolution of Molecular Clouds in a Turbulent Interstellar Medium [PDF]

, 2016
Stars form within molecular clouds in galaxies. Therefore, understanding the formation, evolution and collapse of molecular clouds is critical for understanding galactic evolution.
Ibanez-Mejia, Juan Camilo
core   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

The JDISC Survey: Inner Disk Chemistry of Class I/FS Disks and Tentative Evidence for Early Pebble Drift

The Astronomical Journal
We present the first chemical survey of Class I and flat-spectrum (I/FS) disks using the JWST Mid-Infrared Instrument/Medium-Resolution Spectrometer, targeting 16 sources in the Ophiuchus star-forming region.
Ke Zhang, Andrea Banzatti, Colette Salyk, Abygail Waggoner, Klaus Pontoppidan, María José Colmenares, Ilaria Pascucci, Lucas A. Cieza, Miguel Vioque, Paola Pinilla, Geoffrey A. Blake, Joan Najita, Joe Williams, Sebastiaan Krijt, Till Kaeufer, Jane Huang, Feng Long, Chengyan Xie, Minjae Kim, Eshan Raul, Dary A. Ruíz-Rodríguez, Nicole Arulanantham, Benoît Tabone, Mayank Narang, Karina Mauco   +24 more
doaj   +1 more source

Small-scale physical and chemical structure of diffuse and translucent molecular clouds along the line of sight to Sgr B2

, 2019
International audienceThe diffuse and translucent molecular clouds traced in absorption along the line of sight to strong background sources have so far been investigated mainly in the spectral domain because of limited angular resolution or small sizes ...
Garrod, R. T., A. Belloche, R. T. Garrod, P. Gratier, K. M. Menten, Garrod, R., Wiesemeyer, H., Menten, K. M., H. Wiesemeyer, Giannetti, A., Colombo, D., D. Colombo, Gratier, P., Thiel, V., Winkel, B., H. S. P. Müller, A. Giannetti, B. Winkel, Menten, K., V. Thiel, Belloche, A., Müller, H. S. P., Müller, H.   +22 more
core   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source