Results 131 to 140 of about 42,847 (320)

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Short GMC lifetimes: an observational estimate with the PdBI Arcsecond Whirlpool Survey (PAWS)

open access: yes, 2015
We describe and execute a novel approach to observationally estimate the lifetimes of giant molecular clouds (GMCs). We focus on the cloud population between the two main spiral arms in M51 (the inter-arm region) where cloud destruction via shear and ...
Colombo, Dario   +12 more
core   +3 more sources

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

open access: yesAdvanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan   +19 more
wiley   +1 more source

First Detection of Molecular Gas in the Giant Low Surface Brightness Galaxy Malin 1

open access: yesThe Astrophysical Journal Letters
After over three decades of unsuccessful attempts, we report the first detection of molecular gas emission in Malin 1, the largest spiral galaxy observed to date, and one of the most iconic giant low surface brightness galaxies.
Gaspar Galaz   +19 more
doaj   +1 more source

Model calculations for diffuse molecular clouds [PDF]

open access: yes
A steady state isobaric cloud model is developed. The pressure, thermal, electrical, and chemical balance equations are solved simultaneously with a simple one dimensional approximation to the equation of radiative transfer appropriate to diffuse clouds.
Glassgold, A. E., Langer, W. D.
core   +1 more source

From the warm magnetized atomic medium to molecular clouds

open access: yes, 2008
{It has recently been proposed that giant molecular complexes form at the sites where streams of diffuse warm atomic gas collide at transonic velocities.} {We study the global statistics of molecular clouds formed by large scale colliding flows of warm ...
Audit   +22 more
core   +3 more sources

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Gas-phase Oxygenation and Sulfurization Processes of Fullerene Cations

open access: yesThe Astrophysical Journal
Atomic oxygen and sulfur are known to efficiently react with fullerenes and may thus form a long list of oxygenated and sulfurated fullerene species in the interstellar medium (ISM).
Nian Zhao   +6 more
doaj   +1 more source

Small-scale physical and chemical structure of diffuse and translucent molecular clouds along the line of sight to Sgr B2 [PDF]

open access: hybrid, 2019
Volker Thiel   +9 more
openalex   +1 more source

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