Results 91 to 100 of about 836 (184)

Nickel-catalyzed direct difluoromethylation of aryl boronic acids with BrCF₂H

, 2018
Nickel-catalyzed direct difluoromethylation of aryl boronic acids has been developed with the industrial raw material BrCF2H.
Kang-Jie Bian, Hui-Qi Ni, Yi-Ning Wang, Jie Sheng, Xi-Sheng Wang, Yan Li   +5 more
core   +1 more source

Silver-mediated oxidative C–H difluoromethylation of phenanthridines and 1,10-phenanthrolines

, 2017
An efficient silver-mediated oxidative C–H difluoromethylation of phenanthridines and 1,10-phenanthrolines with TMSCF2H was developed.
Feng-Ling Qing, Sheng-Qing Zhu, Xiu-Hua Xu   +2 more
core   +1 more source

In Situ Generated Fluorinated Iminium Salts for Difluoromethylation and Difluoroacetylation

, 2015
The use of TFEDMA, a fluoroalkyl amino reagent, for the difluoromethylation and difluoroacylation of arenes, heteroarenes, and C–H acidic compounds is reported.
Armen Panossian (1528819), Sergii Pazenok (1528828), Jean-Pierre Vors (1528816), Baptiste Rugeri (1528825), Frédéric R. Leroux (1528813), Etienne Schmitt (1528822)   +5 more
core   +1 more source

Recent Advances in Stereoselecive and Enantioselective Difluoromethylation

The difluoromethyl (CF 2 H) group is a valuable fluorinated motif widely utilized in medicinal and material chemistry owing to its unique physicochemical characteristics.
Zhengguo Chen, Bo Wang, Jing Zhang, Qinghe Liu, Shuaixiang Zhang, Xiaomei Chen   +5 more
core   +1 more source

Copper-Catalyzed Visible-Light-Induced Allylic Difluoromethylation of Unactivated Alkenes Using Difluoroacetic Acid

We herein describe a straightforward allylic difluoromethylation reaction of unactivated alkenes. Compared to cross-couplings of prefunctionalized allylic substrates for the construction of allylic CF2H bonds, this reaction employs readily available ...
Yihan Tang (6851498), Gavin Chit Tsui (1951060), Ziwei Luo (9108927), Xinkan Yang (3949076), Jinlian Wang (317636), Yili Wu (436485)   +5 more
core   +1 more source

Nickel-Boryl-Catalyzed Modular Alkyl Difluoromethylation Enabled by an NMP-Stabilized ICF₂H Reagent. [PDF]

Angew Chem Int Ed Engl
Zhao L, Zhang J, Wei Y, Chen L, Zeng K, Zeng X.   +5 more
europepmc   +1 more source

Direct C-H difluoromethylation of heteroaromatic compounds: emerging methods and developments through 2025. [PDF]

RSC Adv
Hossaini Z, Azizi Z, Niazova A, Soleimani-Amiri S, Zalov AZ, Imanov HA, Huseynova AT, Majeed Alrufaie MM, Vessally E.   +8 more
europepmc   +1 more source

Photoinduced Multicomponent Difluoromethylation of Imines via Iron-Mediated Ligand-to-Metal Charge Transfer. [PDF]

Org Lett
Choi H, Lee J, Lee SB, Han S, Jang J, Hong S.   +5 more
europepmc   +1 more source

Application of fluoroform in trifluoromethylation and difluoromethylation reactions

ARKIVOC, 2017
Cai Zhang
doaj   +1 more source

Enantioselective Difluoromethylation of Unactivated Alkyl Halides via a Formal Nickel(II/IV) Cycle. [PDF]

Nat Catal
Zhao X, Yin L, Yang CJ, Poore AT, Zhang X, Yachuw SC, Wang C, Wang X, Guan H, Krause JA, Cheng MJ, Tian S, Liu W.   +12 more
europepmc   +1 more source