Results 51 to 60 of about 122,665 (274)

Improving Feed Quality Through the Addition of Mangrove Fruit (Sonneratia alba) on Indigofera (Indigofera zollingeriana)

Andalasian Livestock
This study investigated the effects of incorporating tannin-rich mangrove fruit (Sonneratia alba) into Indigofera zollingeriana-based rations on in vitro digestibility and rumen fermentation characteristics. Using a completely randomized design with four
Elihasridas, Roni Pazla, Zaitul Ikhlas, Gusri Yanti, Imana Martaguri, Yelly Fitri, Rani Winardi Wulan Sari   +6 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Effect of Enzymes of Microbial Origin on in vitro Digestibilities of Dry Matter and Crude Protein in Maize

The Journal of Poultry Science, 2003
The effects of supplementation of cellulase, xylanase, pectinase, hemicellulase, glucanase, phytase and protease of microbial origins on digestibilities of crude protein (CP) and dry matter (DM) of maize in vitro were examined in the present study ...
Fuad Saleh, Akira Ohtsuka, Tsuneo Tanaka, Kunioki Hayashi   +3 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Protein and amino acid digestibility: definitions and conventional oro-ileal determination in humans

Frontiers in Nutrition
When assessing protein quality, a correction needs to be made to take into consideration the availability of the amino acids. This correction is based on the digestibility of the amino acids.
Suzanne M. Hodgkinson
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Evaluation of Apparent Nutrient Digestibility of Novel and Conventional Feed Ingredients in Sobaity Seabream (Sparidentex hasta) for Sustainable Aquaculture

Fishes
This study aimed to evaluate the apparent digestibility coefficients (ADCs) for nutrients and energy of seven conventional and alternative feed ingredients (poultry feather meal, fermented feather meal, mealworm meal, defatted black soldier fly ...
Seemab Zehra, Aboobucker S. Abul Kasim, Reda Saleh, Paulo De Mello, Ali Alshaikhi, Joseph Laranja, Yousef Alhafedh, Brett D. Glencross, Majed A. Alghamdi, Asaad Widaa Mohamed   +9 more
doaj   +1 more source

Extrusion pregelatinization improves texture, viscoelasticity and in vitro starch digestibility of mango and amaranth flours

, 2021
Daniel E. Garcia‐Valle, Edith Agama‐Acevedo, María del Carmen Núñez-Santiago, José Álvarez‐Ramírez, Luís A. Bello‐Pérez   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source