Results 61 to 70 of about 270,173 (322)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Evaluation of agro-industrial by-products as protein sources for duck production in the Mekong Delta of Vietnam [PDF]

open access: yes, 2005
This thesis is based on four studies to determine the nutritive value and ileal and total tract amino acid digestibility of agro-industrial by-products, and the effects of inclusion of these by-products in diets on the biological performance of growing ...
Nguyen, Thi Kim Dong
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A note on the chemical composition and in vitro digestibility of contrasting stover components of maize grown in climatically marginal conditions and harvested at differing maturities. [PDF]

open access: yes, 2014
peer-reviewedThis study evaluated the nutritive value of three contrasting components of maize stover (leaf, upper stem, lower stem) at three harvest dates.
Doyle, Evelyn M.   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effects of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers [PDF]

open access: yes, 2007
peer-reviewedThe objective of this experiment was to investigate the effects and interactions of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers.
Cummins, B.   +3 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Improving Feed Quality Through the Addition of Mangrove Fruit (Sonneratia alba) on Indigofera (Indigofera zollingeriana)

open access: yesAndalasian Livestock
This study investigated the effects of incorporating tannin-rich mangrove fruit (Sonneratia alba) into Indigofera zollingeriana-based rations on in vitro digestibility and rumen fermentation characteristics. Using a completely randomized design with four
Elihasridas   +6 more
doaj   +1 more source

Response to dietary tannin challenges in view of the browser/grazer dichotomy in an Ethiopian setting : Bonga sheep versus Kaffa goats [PDF]

open access: yes, 2015
It has been suggested that goats (typical browser) are better adapted to digest tannin-rich diets than sheep (typical grazer). To evaluate this, Bonga sheep and Kaffa goats were used in a 2x3 randomized crossover design with two species, three diets, and
Janssens, Geert   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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