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Mast cells: key players in digestive system tumors and their interactions with immune cells [PDF]

open access: yesCell Death Discovery
Mast cells (MCs) are critical components of both innate and adaptive immune processes. They play a significant role in protecting human health and in the pathophysiology of various illnesses, including allergies, cardiovascular diseases and autoimmune ...
Feihong Shu   +11 more
doaj   +2 more sources

Smoking, alcohol consumption, diabetes, body mass index, and peptic ulcer risk: A two-sample Mendelian randomization study

open access: yesFrontiers in Genetics, 2023
Background: Observational evidence has shown that smoking, alcohol consumption, type 2 diabetes, and body mass index (BMI) are risk factors for peptic ulcer disease (PUD), including gastric ulcer (GU) and duodenal ulcer (DU).
Yi Liu   +6 more
doaj   +1 more source

Expanding the mutational spectrum of ZTTK syndrome: A de novo variant with global developmental delay and malnutrition in a Chinese patient

open access: yesMolecular Genetics & Genomic Medicine, 2023
Background Zhu‐Tokita‐Takenouchi‐Kim (ZTTK, OMIM 617140) syndrome is a severe multisystem developmental disorder characterized by intellectual disability, developmental delay, cortical malformations, epilepsy, visual problems, musculoskeletal ...
Shuo Tang   +13 more
doaj   +1 more source

Predictors and histological effects of preoperative chemoradiotherapy for rectal cancer and control of lateral lymph node metastasis

open access: yesBMC Gastroenterology, 2022
Introduction Standard treatment strategy for low rectal cancer in Japan is different from Western countries. Total mesorectum excision (TME) + lateral lymph node dissection (LLND) is mainly carried out in Japan, whereas neoadjuvant chemoradiotherapy ...
Hiroshi Miyakita   +6 more
doaj   +1 more source

Diffuse cavernous hemangioma of the rectum

open access: yesCirugía y Cirujanos, 2021
Diffuse cavernous hemangioma (DCH) is a rare benign vascular lesion. The rectosigmoid colon is the most common site of this disease. It affects mainly young adults.
Alicia Ruiz de la Hermosa   +2 more
doaj   +1 more source

Total flavonoids of Chrysanthemum indicum L inhibit acute pancreatitis through suppressing apoptosis and inflammation

open access: yesBMC Complementary Medicine and Therapies, 2023
Acute pancreatitis (AP) is one of the most common acute abdomen. Inflammation and apoptosis are closely linked with AP development. Total flavonoids of Chrysanthemum indicum L (TFC) has been proved to inhibit inflammation and apoptosis.
Xiaojuan Yang   +6 more
doaj   +1 more source

Hepatic venous pressure gradient and rebleeding risk of patients with nonalcoholic steatohepatitis cirrhosis after variceal bleeding

open access: yesFrontiers in Medicine, 2023
Background and aimsHepatic venous pressure gradient (HVPG) has a strong predictive value for variceal rebleeding in cirrhotic patients, but the accuracy of HVPG may be compromised in nonalcoholic steatohepatitis (NASH) cirrhosis.
Yiqi Shi   +4 more
doaj   +1 more source

Correlation Analysis of Helicobacter pylori Infection and Digestive Tract Symptoms in Children and Related Factors of Infection

open access: yesIranian Journal of Public Health, 2020
Background: To analyze the correlation between Helicobacter pylori infection and digestive tract symptoms in children and other related factors, and to explore the risk factors of H. pylori infection in children and the expression of inflammatory factors
Xiaohong YU   +5 more
doaj   +1 more source

Trombosis portal aguda en colecistitis incipiente. ¿Una consecuencia de la infección por COVID-19?

open access: yesCirugía y Cirujanos, 2021
La infección por el virus SARS-CoV-2 provoca, además de cuadros respiratorios graves, episodios trombóticos en múltiples localizaciones debido a una mala regulación de la respuesta inmune.
Daniel Rivera-Alonso   +5 more
doaj   +1 more source

TCR-T Immunotherapy: The Challenges and Solutions

open access: yesFrontiers in Oncology, 2022
T cell receptor-engineered T cell (TCR-T) therapy is free from the limit of surface antigen expression of the target cells, which is a potential cellular immunotherapy for cancer treatment.
Yating Liu   +7 more
doaj   +1 more source

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