Results 1 to 10 of about 23,495,921 (382)

Smoking, alcohol consumption, diabetes, body mass index, and peptic ulcer risk: A two-sample Mendelian randomization study

Frontiers in Genetics, 2023
Background: Observational evidence has shown that smoking, alcohol consumption, type 2 diabetes, and body mass index (BMI) are risk factors for peptic ulcer disease (PUD), including gastric ulcer (GU) and duodenal ulcer (DU).
Yi Liu, Yi Liu, Zhihan Xiao, Kun Ye, Kun Ye, Linlin Xu, Yanping Zhang   +6 more
doaj   +1 more source

Expanding the mutational spectrum of ZTTK syndrome: A de novo variant with global developmental delay and malnutrition in a Chinese patient

Molecular Genetics & Genomic Medicine, 2023
Background Zhu‐Tokita‐Takenouchi‐Kim (ZTTK, OMIM 617140) syndrome is a severe multisystem developmental disorder characterized by intellectual disability, developmental delay, cortical malformations, epilepsy, visual problems, musculoskeletal ...
Shuo Tang, Jieyu You, Li Liu, Hongjuan Ouyang, Na Jiang, Jiaqi Duan, Canlin Li, Yanhong Luo, Wenting Zhang, Meizheng Zhan, Chenxi Liu, Gui‐Zhen Lyu, Victor Wei Zhang, Hongmei Zhao   +13 more
doaj   +1 more source

Lactobacillus reuteri in digestive system diseases: focus on clinical trials and mechanisms

Frontiers in Cellular and Infection Microbiology, 2023
Objectives Digestive system diseases have evolved into a growing global burden without sufficient therapeutic measures. Lactobacillus reuteri (L.
Yijing Peng, Yizhe Ma, Zichen Luo, Yifan Jiang, Zhimin Xu, R. Yu   +5 more
semanticscholar   +1 more source

Predictors and histological effects of preoperative chemoradiotherapy for rectal cancer and control of lateral lymph node metastasis

BMC Gastroenterology, 2022
Introduction Standard treatment strategy for low rectal cancer in Japan is different from Western countries. Total mesorectum excision (TME) + lateral lymph node dissection (LLND) is mainly carried out in Japan, whereas neoadjuvant chemoradiotherapy ...
Hiroshi Miyakita, Lin Fung Chan, Kazutake Okada, Hajime Kayano, Masaki Mori, Sotaro Sadahiro, Seiichiro Yamamoto   +6 more
doaj   +1 more source

The Emerging Role of Super-enhancers as Therapeutic Targets in The Digestive System Tumors

International Journal on Biological Sciences, 2023
Digestive system tumors include malignancies of the stomach, pancreas, colon, rectum, and the esophagus, and are associated with high morbidity and mortality.
Xiangpan Li, J. Qu, Xinqi Teng, Haiwen Zhuang, Yinghui Dai, Z. Yang, Q. Qu   +6 more
semanticscholar   +1 more source

Diffuse cavernous hemangioma of the rectum

Cirugía y Cirujanos, 2021
Diffuse cavernous hemangioma (DCH) is a rare benign vascular lesion. The rectosigmoid colon is the most common site of this disease. It affects mainly young adults.
Alicia Ruiz de la Hermosa, Jaime Zorrilla-Ortuzar, Emilio Del Valle-Hernández   +2 more
doaj   +1 more source

NLRP3 inflammasome-induced pyroptosis in digestive system tumors

Frontiers in Immunology, 2023
Programmed cell death (PCD) refers to cell death in a manner that depends on specific genes encoding signals or activities. PCD includes apoptosis, pyroptosis, autophagy and necrosis (programmed necrosis).
Jiexia Wen, Bin Xuan, Yang Liu, Liwei Wang, Li He, Xiangcai Meng, Tao Zhou, Yimin Wang   +7 more
semanticscholar   +1 more source

Abdominal obesity and digestive system cancer: a systematic review and meta-analysis of prospective studies

BMC Public Health, 2023
Background The diagnostic criteria for abdominal obesity are usually waist circumference or waist-to-hip ratio. The magnitude of the risks for cancers of the digestive system and abdominal obesity is unknown. To assess whether abdominal obesity increases
Xue Li, Yajun Lian, Weiwei Ping, Kunbo Wang, Lingyan Jiang, Shaoxia Li   +5 more
semanticscholar   +1 more source

Total flavonoids of Chrysanthemum indicum L inhibit acute pancreatitis through suppressing apoptosis and inflammation

BMC Complementary Medicine and Therapies, 2023
Acute pancreatitis (AP) is one of the most common acute abdomen. Inflammation and apoptosis are closely linked with AP development. Total flavonoids of Chrysanthemum indicum L (TFC) has been proved to inhibit inflammation and apoptosis.
Xiaojuan Yang, Yun Liu, Chao Zhong, Jia Hu, Song Xu, Ping Zhang, Ling He   +6 more
doaj   +1 more source

Piezo1 in Digestive System Function and Dysfunction

International Journal of Molecular Sciences, 2023
Piezo1, a non-selective cation channel directly activated by mechanical forces, is widely expressed in the digestive system and participates in biological functions physiologically and pathologically.
Jing He, Xiaotian Xie, Zhuanglong Xiao, W. Qian, Lei Zhang, X. Hou   +5 more
semanticscholar   +1 more source