Results 61 to 70 of about 25,425,556 (293)

Plant cell walls: impact on nutrient bioaccessibility and digestibility [PDF]

, 2020
Cell walls are important structural components of plants, affecting both the bioaccessibility and subsequent digestibility of the nutrients that plant-based foods contain.
Edwards, Cathrina H., Grundy, Myriam M.-L., Holland, Claire, Ryden, Peter   +3 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Special Chimeric Antigen Receptor (CAR) Modifications of T Cells: A Review

Frontiers in Oncology, 2022
Chimeric antigen receptor (CAR) -T cell therapy has become one of the hot topics in tumor immunity research in recent years. Although CAR-T cell therapy is highly effective in treating hematological malignancies, there are numerous obstacles that prevent
Lele Miao, Lele Miao, Juan Zhang, Binjie Huang, Binjie Huang, Zhengchao Zhang, Zhengchao Zhang, Song Wang, Song Wang, Futian Tang, Muzhou Teng, Muzhou Teng, Yumin Li, Yumin Li, Yumin Li   +14 more
doaj   +1 more source

CircRNAs: a new target for the diagnosis and treatment of digestive system neoplasms

Cell Death and Disease, 2021
A circRNA is a type of endogenous noncoding RNA that consists of a closed circular RNA molecule formed by reverse splicing; these RNAs are widely distributed in a variety of biological cells. In contrast to linear RNAs, circRNAs have no 5′ cap or 3′ poly(
Jie Li, Qiang Xu, Zi-jian Huang, Ning Mao, Zhitao Lin, Long Cheng, Bei Sun, Gang Wang   +7 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Nomenclature of appendiceal mucinous lesions according to the 2019 WHO Classification of Tumors of the Digestive System.

The Turkish Journal of Gastroenterology, 2020
BACKGROUND/AIMS To analysis the appendiceal mucinous lesions according to the World Health Organization (WHO) 2010 and 2019 classification of tumors of the digestive system (non-neuroendocrine tumors of the appendix vermiformis) Materials and Methods ...
C. Koç, S. Akbulut, A. Akatlı, Emine Türkmen Şamdancı, A. Tunçer, S. Yılmaz   +5 more
semanticscholar   +1 more source

Glycocalyx production in teleosts [Translation from: Verhandlungen der Deutschen Zoologischen Gesellschaft, p.286, 1970] [PDF]

, 1978
Shielding the organism against harmful effects from the environment is one of the most important tasks of the outer covering of all animals. The epidermis of primarily aquatic organisms and the epithelia of organs which are exposed to water, such as the ...
Bereiter-Hahn, J., Schwerdtfeger, W. K.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies

Systematic Reviews, 2022
Background and objectives Cancer morbidity and mortality rates remain high, and thus, at present, considerable efforts are focused on finding drugs with higher sensitivity against tumor cells and fewer side effects. Disulfiram (DSF), as an anti-alcoholic
Ling Wang, Yang Yu, Cong Zhou, Run Wan, Yumin Li   +4 more
doaj   +1 more source

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. [PDF]

, 2017
During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained
Darbellay, Fabrice, Duboule, Denis, Mascrez, Bénédicte, Necsulea, Anamaria, Zakany, Jozsef   +4 more
core   +1 more source