Results 61 to 70 of about 22,831,370 (389)

Biochemical characterization of digestive carbohydrases from Xanthogaleruca luteola and inhibition of its α-amylase by inhibitors extracted from the common bean [PDF]

open access: yes, 2011
Xanthogaleruca luteola Müll. (Col.: Chrysomelidae) is a major urban insect pest on elm trees in Iran. Digestion in the alimentary canal of the elm leaf beetle is facilitated by some carbohydrases which are responsible for the digestion of ...
Ghadamyari Mohammad   +3 more
core   +1 more source

Special Chimeric Antigen Receptor (CAR) Modifications of T Cells: A Review

open access: yesFrontiers in Oncology, 2022
Chimeric antigen receptor (CAR) -T cell therapy has become one of the hot topics in tumor immunity research in recent years. Although CAR-T cell therapy is highly effective in treating hematological malignancies, there are numerous obstacles that prevent
Lele Miao   +14 more
doaj   +1 more source

CircRNAs: a new target for the diagnosis and treatment of digestive system neoplasms

open access: yesCell Death and Disease, 2021
A circRNA is a type of endogenous noncoding RNA that consists of a closed circular RNA molecule formed by reverse splicing; these RNAs are widely distributed in a variety of biological cells. In contrast to linear RNAs, circRNAs have no 5′ cap or 3′ poly(
Jie Li   +7 more
semanticscholar   +1 more source

Prognostic nutritional index as a prognostic biomarker for gastrointestinal cancer patients treated with immune checkpoint inhibitors

open access: yesFrontiers in Immunology, 2023
ObjectiveOur study represents the first meta-analysis conducted to evaluate the prognostic utility of the baseline prognostic nutritional index (PNI) in patients with gastrointestinal cancer (GIC) who received immune checkpoint inhibitor (ICI) therapy ...
Lilong Zhang   +13 more
doaj   +1 more source

Penerapan Model Pembelajaran Kooperatif Tipe Numbereded Heads Together (NHT) pada Konsep Sistem Pencernaan Makanan pada Manusia di Kelas IV SD Negeri Mandalasari 1 Kecamatan Puspahiang Kabupaten Tasikmalaya. [PDF]

open access: yes, 2016
Research aims to understand match / the accuracy of learning model cooperative type Numbered heads & together ( nht in learning the concept of digestive system food on human beings in fourth grade land mandalasari 1 kecamatan puspahiang the market.
Nuryadin, E. (Egi)
core   +2 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies

open access: yesSystematic Reviews, 2022
Background and objectives Cancer morbidity and mortality rates remain high, and thus, at present, considerable efforts are focused on finding drugs with higher sensitivity against tumor cells and fewer side effects. Disulfiram (DSF), as an anti-alcoholic
Ling Wang   +4 more
doaj   +1 more source

The glucagon-like Peptide-2 [PDF]

open access: yes, 2011
Multiple peptide hormones produced within the gastrointestinal system act also in the central nervous system and aid in the regulation of energy homeostasis and metabolism. The list of these peptides is progressively increasing and includes glucagon-like
Mule, Flava
core  

Plant cell walls: impact on nutrient bioaccessibility and digestibility [PDF]

open access: yes, 2020
Cell walls are important structural components of plants, affecting both the bioaccessibility and subsequent digestibility of the nutrients that plant-based foods contain.
Edwards, Cathrina H.   +3 more
core   +2 more sources

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