Results 71 to 80 of about 22,831,370 (389)
Supplemental Digital Content is available in the text. Background: The worldwide outbreak of COVID-19 infected millions of people. Some patients had gastrointestinal (GI) symptoms, abnormal liver function, digestive system disease and liver disease. Aim:
Zi-yuan Dong+4 more
semanticscholar +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield+3 more
wiley +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source
We report the first known case of a retroperitoneal leiomyosarcoma that presented with an endoscopically defined source of gastrointestinal bleeding in the colon. A 68-year-old male with a history of diverticulosis, hypertension, and hypercholesterolemia
Dominic G. Ventura+2 more
doaj +1 more source
Objectives: To analyze the clinical and imaging features of acute ischemic stroke (AIS) related to gastrointestinal malignant tumor, and to explore the prognostic factors.Methods: Clinical data of consecutive patients with gastrointestinal malignant ...
Yating Liu+7 more
doaj +1 more source
Glycocalyx production in teleosts [Translation from: Verhandlungen der Deutschen Zoologischen Gesellschaft, p.286, 1970] [PDF]
Shielding the organism against harmful effects from the environment is one of the most important tasks of the outer covering of all animals. The epidermis of primarily aquatic organisms and the epithelia of organs which are exposed to water, such as the ...
Bereiter-Hahn, J., Schwerdtfeger, W. K.
core
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi+5 more
wiley +1 more source
Roles of the CXCL8-CXCR1/2 Axis in the Tumor Microenvironment and Immunotherapy
In humans, Interleukin-8 (IL-8 or CXCL8) is a granulocytic chemokine with multiple roles within the tumor microenvironment (TME), such as recruiting immunosuppressive cells to the tumor, increasing tumor angiogenesis, and promoting epithelial-to ...
Zhi-Jian Han+5 more
doaj +1 more source
Outreach Education: Making Neuroscience Readily Available for Rural Students and Communities of Alaska [PDF]
WHAT is neuroscience? Neuroscience is the scientific study of the structure or function of the nervous system and brain. To get a grasp on the vast study of neuroscience, first think of the human body and how complex it is. Think of the skeletal system
Ellison, Ariel
core
New Coronavirus Infection (COVID-19) and Digestive System
Aim. The study reviews current evidence on digestive system lesions provoked by the new COVID-19 coronavirus infection.Key points. Alongside the destructive impact on respiratory system, COVID-19 manifests itself in gastrointestinal symptoms (nausea ...
органов пищеварения+9 more
semanticscholar +1 more source