Results 11 to 20 of about 207,794 (266)

New Interleukin-23 Antagonists’ Use in Crohn’s Disease

Pharmaceuticals
Crohn’s disease (CD) is a chronic inflammatory condition of the digestive tract, driven by an imbalance in immune system regulation, where proinflammatory interleukin-23 (IL-23) plays an essential role.
Laura Biskup, Jan Semeradt, Jagoda Rogowska, Wiktoria Chort, Łukasz Durko, Ewa Małecka-Wojciesko   +5 more
doaj   +1 more source

Prevalence and Molecular Characterization of Defective DNA Mismatch Repair in Small-bowel Carcinoma in a Japanese Hospital-based Population

Journal of the Anus, Rectum and Colon, 2020
Objectives: To investigate the prevalence and molecular characteristics of defective DNA mismatch repair (dMMR) in small-bowel carcinoma (SBC) in a Japanese-hospital population.
Tetsuya Ito, Hideyuki Ishida, Okihide Suzuki, Noriyasu Chika, Kunihiko Amano, Keiichiro Ishibashi, Nao Kamae, Yuhki Tada, Kiwamu Akagi, Hidetaka Eguchi, Yasushi Okazaki   +10 more
doaj   +1 more source

Treatment Strategies for Chronic Pancreatitis (CP)

Pharmaceuticals
Chronic pancreatitis (CP) and autoimmune pancreatitis (AIP) are diseases with overlapping features, both requiring complex management strategies. CP is characterized by pancreatic exocrine insufficiency (PEI) and pain, with treatment focused on symptom ...
Katarzyna Tłustochowicz, Agnieszka Krajewska, Adrianna Kowalik, Ewa Małecka-Wojciesko   +3 more
doaj   +1 more source

The position of a duodenal diverticulum in the area of the major duodenal papilla and its potential clinical implications

Folia Morphologica, 2021
BACKGROUND: Although duodenal diverticula are associated with less frequent pathology than the colonic diverticula in the large intestine, their periampullary position may have significant clinical implications.
E. Jakubczyk, M. Pazurek, A. Mokrowiecka, B. Woźniak, E. Małecka-Panas, M. Podgórski, M. Polguj, M. Topol   +7 more
doaj   +1 more source

Celiac Disease—Narrative Review on Progress in Celiac Disease

Foods
Celiac disease is defined as a systemic immunological disorder caused by gluten (gliadin and other prolamin) in genetically predisposed individuals, who present with a variety of gluten-dependent symptoms, specific antibodies, the presence of the HLA DQ2
Marek K. Kowalski, Danuta Domżał-Magrowska, Ewa Małecka-Wojciesko   +2 more
doaj   +1 more source

Immunonutrition before esophagectomy: Impact on immune surveillance mechanisms

Tumor Biology, 2017
Preoperative oral immunonutrition was demonstrated to improve immune response and to decrease the infection rate in patients with cancer. This study aimed to assess how immunonutrition could influence the immune cell response in the mucosal ...
Marco Scarpa, Andromachi Kotsafti, Matteo Fassan, Melania Scarpa, Francesco Cavallin, Teresa Nardi, Eleonora Pinto, Rita Alfieri, Matteo Cagol, Marco Agostini, Massimo Rugge, Ignazio Castagliuolo, Carlo Castoro   +12 more
doaj   +1 more source

Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer

International Journal of Translational Medicine
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with poor survival even after surgical resection. Clinical stages include resectable (R-PDAC), borderline resectable (BR-PDAC), locally advanced, and metastatic disease ...
Julia Groszewska, Michał Romaniuk, Ewa Małecka-Wojciesko   +2 more
doaj   +1 more source

Author Correction: Cholecystectomy - a potential selection bias in studies assessing the metabolic effects of bariatric surgeries

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Natasha Mendonça Machado, Camila de Siqueira Cardinelli, Tong Shen, Marco Aurélio Santo, Raquel Susana Torrinhas, Dan Linetzky Waitzberg   +5 more
doaj   +1 more source

Feature selection with a genetic algorithm can help improve the distinguishing power of microbiota information in monozygotic twins' identification

Frontiers in Microbiology, 2023
IntroductionPersonal identification of monozygotic twins (MZT) has been challenging in forensic genetics. Previous research has demonstrated that microbial markers have potential value due to their specificity and long-term stability.
Guangping Fu, Guanju Ma, Shujie Dou, Qian Wang, Lihong Fu, Xiaojing Zhang, Chaolong Lu, Bin Cong, Bin Cong, Shujin Li   +9 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source