Results 61 to 70 of about 451,596 (341)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Information seeking in the Humanities: physicality and digitality [PDF]
, 2008 This paper presents a brief overview of a research project that is examining the information seeking practices of humanities scholars. The results of this project are being used to develop digital resources to better support these work activities ...
Blandford, A. +4 more
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Talking With Scholars: Developing a Research Environment for Oral History Collections [PDF]
, 2014 Scholars are yet to make optimal use of Oral History collections. For the uptake of digital research tools in the daily working practice of researchers, practices and conventions commonly adhered to in the subfields in the humanities should be taken into
de Jong, Franciska +3 more
core +5 more sources
Introduction: Digital Humanities, Public Humanities
NANO, 2014 NANO: New American Notes Online: An Interdisciplinary Academic Journal for Big Ideas in a Small World. This special issue shows how both public and digital humanities research can be rendered more persuasive through engagement with cultures beyond the ...
Alex Christie +3 more
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o-bib. Das offene Bibliotheksjournal, 2017 Der Beitrag geht von der Beobachtung aus, dass Bibliotheken bisher zwar die Themen E‑Science und Forschungsdaten in ihre Überlegungen hinsichtlich spezifischer Angebote zur Informationskompetenz einbezogen haben. Aber obwohl Bibliotheken über ein breites
Marcus Schröter
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Digital Humanities and Librarians: A Team-Based Approach to Learning [PDF]
, 2015 This chapter details the development and implementation of an Introduction to Digital Humanities course (ENGL 695) at Kansas State University (K-State).
Crosby, Mark, Hoeve, Casey, Pankl, Lis
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Visualization in digital humanities
大数据, 2022 The development of information technology has promoted the generation of a new scientific research paradigm.Social sciences and humanities have gradually developed a data-driven research method in recent years.From the perspective of visualization, the ...
Yuchu LUO +6 more
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