Results 61 to 70 of about 2,680,690 (272)
Digital Literacy Key Performance Indicators for Sustainable Development
Social Inclusion, 2020 The concept of digital literacy has been defined in numerous ways over the last two decades to incorporate rapid technological changes, its versatility, and to bridge the global digital divide.
Danica Radovanović +8 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
‘e-fatura’ - Estudo misto com participantes Seniores num projeto Municipal em Viseu
Páginas a&b, 2020 The use of Information and Communication Technologies (ICT) is now democratized in the information society, however there are some age brackets that use less, such as senior citizens over the age of 65. Although the use of ICT among the senior population
Manuel Monteiro Barbosa +1 more
doaj +1 more source
Access space and digital outreach trainers case study [PDF]
, 2011 This paper evaluates a situation where two organisations, in the field of encouraging digital inclusion, targeted the same population with the same intent, but with different modes of engagement.
Walton, John
core
A systematic review of digital interventions for improving the diet and physical activity behaviors of adolescents [PDF]
, 2017 Many adolescents have poor diet and physical activity behaviors, which can lead to the development of noncommunicable diseases in later life. Digital platforms offer inexpensive means of delivering health interventions, but little is known about their ...
Baird, Janis +10 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Technological appropriation for the effective incorporation of open educational resources
Apertura, 2017 This article is based on a research which sought to identify the technological appropriation of five teachers who excel using technologies, according to their institute’s directors, to incorporate open educational resources (OER) to support educative ...
Fidel Ernesto Contreras Maradey +1 more
doaj +1 more source
Student experiences of technology integration in school subjects: A comparison across four middle schools [PDF]
, 2018 This research examined student perspectives on their in-school, subject specific, technology use in four U.S. public schools. Considering students’ perspectives may provide a significant reframing of adult-created rhetoric of the utopian power of digital
Hughes, Joan E., Read, Michelle F.
core +1 more source
The promotion of digital inclusion through MOOC design and use: a literature review [PDF]
, 2015 The use of Massive Open Online Courses (MOOCs) is being increasingly equated as a viable option by several educational shareholders in the scope of many scientific areas; nevertheless, research as to its potentialities in terms of digital (and ...
Balula, Ana
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source