Results 61 to 70 of about 2,644,704 (272)
The promotion of digital inclusion through MOOC design and use: a literature review [PDF]
, 2015 The use of Massive Open Online Courses (MOOCs) is being increasingly equated as a viable option by several educational shareholders in the scope of many scientific areas; nevertheless, research as to its potentialities in terms of digital (and ...
Balula, Ana
core +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Student experiences of technology integration in school subjects: A comparison across four middle schools [PDF]
, 2018 This research examined student perspectives on their in-school, subject specific, technology use in four U.S. public schools. Considering students’ perspectives may provide a significant reframing of adult-created rhetoric of the utopian power of digital
Hughes, Joan E., Read, Michelle F.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Older adults’ digital inclusion: New challenges for Lithuanian social policy [PDF]
SHS Web of ConferencesLithuania, as most of the EU countries, has an aging population. At the beginning of 2019, there were 552.4 thousand elderly people (aged 65 and older), or 19.8 per cent of the total resident population.
Zemaitaityte Irena +3 more
doaj +1 more source
Incorporated citizens: multinational high-tech companies and the BoP [PDF]
, 2012 In this article, I examine HP’s e-Inclusion program and its implementation in India to show how the high-tech industry’s efforts to alleviate poverty profitably are guided by C. K. Prahalad’s ideas about the Bottom of the Pyramid (BoP), and are framed as
Schwittay, Anke
core
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Digital inclusion : more and more in the center of social inclusion [PDF]
, 2005 Discute-se no início o que seria inclusão social, questionando a tendência de reduzir inclusão social à inclusão marginal. O pobre é acomodado dentro do sistema, mas em sua margem. Esta é a tendência predominante na política social neoliberal.
Demo, Pedro
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source