Results 81 to 90 of about 3,753,769 (363)
International Journal of Librarianship, 2017 This article reviews the influence that massive digital libraries like the HathiTrust Digital Library can have on local, smaller institutions’ digitization, preservation, and curation programs.
Heidi M. Winkler, Joy M. Perrin
doaj +1 more source
The LIFE2 final project report [PDF]
, 2008 Executive summary: The first phase of LIFE (Lifecycle Information For E-Literature) made a major contribution to understanding the long-term costs of digital preservation; an essential step in helping institutions plan for the future.
Ayris, P. +5 more
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Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Digital Preservation Education in iSchools [PDF]
, 2010 This poster investigates digital preservation education in the iSchool caucus. The project identifies core concepts addressed in digital preservation coursework in iSchools and identifies possible areas for curriculum development.
Costello, Kaitlin
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Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Digital preservation: concepts and methods
Knjižnica, 2010 The paper is a review of digital preservation theory and practice. Main concepts, standards and recommendations in this field as well methods implemented by digital archives (libraries and archival institutions responsible for digital preservation) are ...
Alenka Kavčič-Čolić
doaj +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Code4Lib Journal, 2013 SPRUCE digital preservation mashups are a series of unique events that are being organized in the United Kingdom to bring together digital preservation practitioners and developers to work on real-world digital preservation challenges.
Edward M. Corrado
doaj
A Problem of Long - Term Digital Preservation: Difference in Humanities and Natural Sciences
Bibliotheca Lituana, 2014 The article deals with the requirements and needs for long-term digital preservation in different areas of scholarly work. The concept of long-term digital preservation is introduced by comparing it to digitization and archiving concepts and defined with
Elena Macevičiūtė
doaj +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source