Results 61 to 70 of about 2,641,125 (304)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Effects of common image manipulations on diagnostic performance in digital pathology: human study [PDF]

open access: yes, 2013
A very recent work of Ref.[1] studied the effects of image manipulation and image degradation on the perceived attributes of image quality (IQ) of digital pathology slides.
Kumcu, Asli   +5 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Open loop digital frequency multiplier [PDF]

open access: yes, 1977
An open loop digital frequency multiplier is described which has a multiplied output synchronized to low frequency clock pulse. The system includes a multistage digital counter which provides a pulse output as a function of an integer divisor.
Moore, R. C.
core   +1 more source

Shot Noise in Digital Holography [PDF]

open access: yes, 2010
We discuss on noise in heterodyne holography in an off-axis configuration. We show that, for a weak signal, the noise is dominated by the shot noise on the reference beam.
A. Macovsky   +22 more
core   +5 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The Design of a System Architecture for Mobile Multimedia Computers [PDF]

open access: yes, 2000
This chapter discusses the system architecture of a portable computer, called Mobile Digital Companion, which provides support for handling multimedia applications energy efficiently.
Havinga, Paul Johannes Mattheus
core   +3 more sources

Advanced content-based semantic scene analysis and information retrieval: the SCHEMA project [PDF]

open access: yes, 2003
The aim of the SCHEMA Network of Excellence is to bring together a critical mass of universities, research centers, industrial partners and end users, in order to design a reference system for content-based semantic scene analysis, interpretation and ...
E. Izquierdo   +7 more
core   +2 more sources

„Digital complete denture – reference protocol“

open access: yesInternational Dental Journal
INTRODUCTION: The conventional process of fabricating complete dentures consists of 5 to 6 clinical and laboratory phases, which involve multiple visits of edentulous patients to the dental office. Additionally, in the conventional process of fabrication, there are mechanical weaknesses of the acrylic, technological deficiencies of compression-molding ...
Robert Ćelić   +3 more
openaire   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

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