Results 51 to 60 of about 2,641,125 (304)

[Digital] Archive [PDF]

open access: yes, 2014
The study of what is collectively labeled New Media —the cultural and artistic practices made possible by digital technology—has become one of the most vibrant areas of scholarly activity and is rapidly turning into an established academic field, with ...
Harris, Katherine D
core   +1 more source

Digital-analog quantum simulation of generalized Dicke models with superconducting circuits [PDF]

open access: yes, 2017
We propose a digital-analog quantum simulation of generalized Dicke models with superconducting circuits, including Fermi-Bose condensates, biased and pulsed Dicke models, for all regimes of light-matter coupling. We encode these classes of problems in a
Lamata, Lucas
core   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Towards Building Reuse-Based Digital Libraries for National Universities in Patagonia

open access: yesJournal of Computer Science and Technology, 2018
This article presents a case study exploring the use of software product lines and reference models as mechanisms of a reuse-based design process to build digital libraries.
Alejandra Cechich   +3 more
doaj   +1 more source

Digital Theology: Is the Resurrection Virtual? [PDF]

open access: yes, 2012
Many recent writers have developed a rich system of theological concepts inspired by computers. This is digital theology. Digital theology shares many elements of its eschatology with Christian post-millenarianism.
Steinhart, Eric
core  

‘Digital by Default’ and the ‘hard to reach’ : Exploring solutions to digital exclusion in remote rural areas [PDF]

open access: yes, 2016
The research reported here is supported by the award made by the RCUK Digital Economy programme to the dot.rural Digital Economy Hub [award reference: EP/G066051/1].Peer ...
Fairhurst, Gorry   +3 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Design approach for a microprocessor-based GPS time transfer receiver [PDF]

open access: yes, 1982
The design concept and characteristics of a self-contained microprocessor-based Global Positioning System time transfer receiver is described. A prototype of this unit is currently in the test phase. It employs two-bit digital baseband correlation rather
Ould, P. C., Vanwechel, R. J.
core   +1 more source

Digital Innovation Through Partnership Between Nature Conservation Organisations and Academia : A Qualitative Impact Assessment [PDF]

open access: yes, 2015
We would like to thank all interviewees for sharing their experiences of working with academics, and the guest editor and three anonymous reviewers for valuable comments on earlier versions of the work. The research in this paper is supported by the RCUK
Edwards, Peter   +3 more
core   +2 more sources

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