Results 51 to 60 of about 1,513,863 (295)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Application of terrestrial‚ 'structure-from-motion' photogrammetry on a medium-size Arctic valley glacier: potential, accuracy and limitations [PDF]

, 2014
Terrestrial photogrammetry was the standard method for mapping high mountain terrain in the early days of mountain cartography, until it was replaced by aerial photogrammetry and airborne laser scanning.
Binder, Daniel, Boffi, Geo, Hynek, Bernhard, Verhoeven, Geert, Wolfgang, Schöner   +4 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Parameter identification of a mechanical ductile damage using Artificial Neural Networks in sheet metal forming. [PDF]

, 2013
In this paper, we report on the developed and used of finite element methods, have been developed and used for sheet forming simulations since the 1970s, and have immensely contributed to ensure the success of concurrent design in the manufacturing ...
Abbassi, Fethi, Belhadj, Touhami, Mistou, Sébastien, Zghal, Ali   +3 more
core   +2 more sources

Digital Surface Modelling by Airborne Laser Scanning and Digital Photogrammetry for Glacier Monitoring [PDF]

The Photogrammetric Record, 2001
The research described in this paper is part of a Swiss National Science Foundation project on ”Mass Balance Determination of Glaciers with the Use of State‐of‐the‐art Remote Sensing Methods and a Numerical Flow Model”. The remote sensing methods involve automated processing of aerial images and laser scanning and aim to produce glacier surface models ...
Baltsavias, Emmanuel P., Favey, Etienne, Bauder, Andreas Christian, Bösch, Hermann, Pateraki, Maria N.   +4 more
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Identification and classification of surface defects for digital twin models of the workpiece.

PLoS ONE
Workpiece surface defect detection is an indispensable part of intelligent production. The surface information obtained by traditional 2D image detection has some limitations due to the influence of environmental light factors and part complexity ...
Ligang Qu, Xuesong Huang, Danya Zhang, Zeng Chen   +3 more
doaj   +1 more source

Robust Automatic Generation of True Orthoimages From Very High-Resolution Panchromatic Satellite Imagery Based on Image Incidence Angle for Occlusion Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
Orthoimages have proven to provide useful reference data for a variety of geospatial applications. Their improved versions, true orthoimages, are even more valuable as they have been adjusted also for high objects. Even though true orthoimages have been&#
Ales Marsetic
doaj   +1 more source

3D printing dimensional calibration shape: Clebsch Cubic

, 2015
3D printing and other layer manufacturing processes are challenged by dimensional accuracy. Several techniques are used to validate and calibrate dimensional accuracy through the complete building envelope. The validation process involves the growing and
A Cayley, A Clebsch, A Clebsch, AB Coble, D Cox, G Salmon, L Cremona   +6 more
core   +1 more source