Results 11 to 20 of about 6,589 (233)

Destructive effect of digitalis overdose on blood-brain barrier in rats; an experimental study [PDF]

Journal of Research in Clinical Medicine, 2020
Introduction: Cardiac glycosides are widely used in critical cardiac diseases despite their unexplained mechanisms on cardio-respiratory system and other autonomic complications within both intra-uterine and post-natal life.
Mehmet Nuri Kocak, Ozgur Caglar, Dilek Destegul, Kemal Alp Nalci, Sevilay Ozmen, Mehmet Dumlu Aydin   +5 more
doaj   +1 more source

Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea

PLoS ONE, 2023
The medicinal plant Digitalis purpurea produces cardiac glycosides that are useful in the pharmaceutical industry. These bioactive compounds are in high demand due to ethnobotany’s application to therapeutic procedures.
Fatemeh Amiri, Ali Moghadam, Ahmad Tahmasebi, Ali Niazi   +3 more
doaj   +2 more sources

High-resolution tandem mass spectrometry dataset reveals fragmentation patterns of cardiac glycosides in leaves of the foxglove plants

Data in Brief, 2020
Cardiac glycosides, steroid derivatives extracted from the foxglove plants, have been used for the treatment of heart failure since the 18th century. A method based on liquid chromatography coupled with high-resolution tandem mass spectrometry (LC/MS2 ...
Baradwaj Gopal Ravi, Mary Grace E. Guardian, Rebecca Dickman, Zhen Q. Wang   +3 more
doaj   +1 more source

Plant Toxins: Poison or Therapeutic?

CHIMIA, 2020
Many plants that are classed as poisonous also have therapeutic uses, and this is illustrated using members of the Drimia and Digitalis genera which are sources of cardiac glycosides.
Catherine E. Housecroft
doaj   +1 more source

Studies on Digitalis Glycosides

YAKUGAKU ZASSHI, 1960
Daisuke Satoh, Takayuki Wada
openaire   +3 more sources

A suicide attempt by ingestion of oleander leaves and treatment with digoxin-specific Fab antibody fragments

Arhiv za Higijenu Rada i Toksikologiju, 2023
Natural cardiac glycosides have positive inotropic heart effects but at high, toxic doses they can cause life-threatening cardiac arrhythmias. Here we present the first Croatian case of a 16-year-old girl who attempted suicide by eating dried oleander ...
Kovačević Tanja, Polić Branka, Ardalić Tatjana Ćatipović, Petrović Davor, Stričević Luka, Rogulj Maja, Markić Joško   +6 more
doaj   +1 more source

Comprehensive analysis of alternative splicing in Digitalis purpurea by strand-specific RNA-Seq. [PDF]

PLoS ONE, 2014
Digitalis purpurea (D. purpurea) is one of the most important medicinal plants and is well known in the treatment of heart failure because of the cardiac glycosides that are its main active compounds. However, in the absence of strand specific sequencing
Bin Wu, Fengmei Suo, Wanjun Lei, Lianfeng Gu   +3 more
doaj   +1 more source

Catheter Ablation Is Associated With a Decrease in Major Adverse Cardiovascular Events and All-Cause Mortality in Patients With Atrial Fibrillation and Obstructive Sleep Apnea. [PDF]

J Cardiovasc Electrophysiol
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a common risk factor for the development and progression of atrial fibrillation (AF). Whether catheter ablation for AF management in patients with coexisting OSA yields survival benefit remains unclear.
Bidaoui G, Massad C, Abi-Rached J, Abdelmaksoud A, Toraih E, Abou-Khalil M, Bsoul M, Atasi M, Pandey A, Marrouche N, and other members of the TRIAD Team, Menassa Y, Feng H, Rao S, Lim C, Assaf A, Younes H.   +16 more
europepmc   +2 more sources

Cardiac glycosides and breast cancer risk: A systematic review and meta-analysis of observational studies [PDF]

, 2017
Cardiac glycosides are phytoestrogens and have been linked to the risk of estrogen sensitive cancers such as uterus cancer. However, the association between use of cardiac glycosides and risk of breast cancer remains unclear.
Ahern, Ahern, Aromaa, Beral, Biggar, Biggar, Biggar, Braunstein, Collaborative Group on Hormonal Factors in Breast Cancer, Couraud, Cuzick, Danielson, DerSimonian, Dickey, Friedman, Hartz, Haux, Higgins, International Agency for Research on Cancer, Joint Formulary Committee, Kirkwood, Rifka, Rifka, Rossouw, Schneeweiss, Stenkvist, Stenkvist   +26 more
core   +1 more source

Digitalis for treatment of heart failure in patients in sinus rhythm [PDF]

, 2014
<b>Background</b><p></p> Digitalis glycosides have been in clinical use for the treatment of heart failure (HF) for longer than 200 years.
Dans, Antonio L, Guyatt, Gordon H, Hood, Jr., William B, Jaeschke, Roman, McMurray, John JV   +4 more
core   +1 more source