Results 21 to 30 of about 5,715 (204)
Natural cardiac glycosides have positive inotropic heart effects but at high, toxic doses they can cause life-threatening cardiac arrhythmias. Here we present the first Croatian case of a 16-year-old girl who attempted suicide by eating dried oleander ...
Kovačević Tanja +6 more
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Variation in the chemical profiles of three foxglove species in the central Balkans
The aim of this study was to determine intra- and interspecies variation in the qualitative and quantitative composition of methanol-soluble metabolites in the leaves of three Digitalis species (D. lanata, D. ferruginea, and D.
Uroš Gašić +15 more
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Comprehensive analysis of alternative splicing in Digitalis purpurea by strand-specific RNA-Seq. [PDF]
Digitalis purpurea (D. purpurea) is one of the most important medicinal plants and is well known in the treatment of heart failure because of the cardiac glycosides that are its main active compounds. However, in the absence of strand specific sequencing
Bin Wu +3 more
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Duckweeds: Model organisms for research on plant sterols and steroids. [PDF]
Duckweeds (Lemnaceae), the fastest‐growing angiosperms and promising vegan protein source, offer a powerful model to address key questions in plant physiology. This article highlights their potential for dissecting the biosynthesis and function of phytosterols, sterol conjugates, brassinosteroids, and specialized steroidal metabolites, such as ...
Klein J, Appenroth KJ, Sree KS.
europepmc +2 more sources
Effects of sacubitril/valsartan in the PARADIGM-HF Trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) according to background therapy [PDF]
Background—In the PARADIGM-HF trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure), the angiotensin receptor neprilysin inhibitor sacubitril/valsartan was more effective than the ...
Gong, Jianjian +11 more
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Cardiac glycosides and breast cancer risk: A systematic review and meta-analysis of observational studies [PDF]
Cardiac glycosides are phytoestrogens and have been linked to the risk of estrogen sensitive cancers such as uterus cancer. However, the association between use of cardiac glycosides and risk of breast cancer remains unclear.
Ahern +26 more
core +1 more source
This post hoc analysis of an Italian active pharmacovigilance study describes pharmacological differences of ADEs leading to emergency department (ED) visits and hospitalization in women and men.
Giada Crescioli +11 more
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Endogenous Digitalis-like Factors: An Overview of the History
The sodium pump is a ubiquitous cell surface enzyme, a Na, K ATPase, which maintains ion gradients between cells and the extracellular fluid (ECF). The extracellular domain of this enzyme contains a highly conserved binding site, a receptor for a plant ...
Vardaman eBuckalew
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Cardiac Glycoside Plants Self-Poisoning
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander, Convallaria majalis (lily of the valley), Strophanthus gratus, etc.
Radenkova-Saeva J., Atanasov P.
doaj +1 more source
The present study was performed using tissue culture technique purpose of knowing the effect of using precursors in the presence of TDZ semi–cytokinin and maltos sugar on the cardiac glycosides constituents shoots of Digitalis purpurea digitoxin ...
AL–Khateeb H. Ekbal, Awad J. Zeinab
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