A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells [PDF]
, 2013 Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium oleander has been used in traditional medicine for treating several disorders including cancer, and extracts from the leaves of this ...
Burgos Morón, Estefanía +4 more
core +2 more sources
Case Reports in Psychiatry, 2014 Acute digoxin intoxication is a life-threating condition associated with severe cardiotoxicity. Female gender, age, low lean body mass, hypertension, and renal insufficiency may worsen the prognosis.
Diletta Sabatini +4 more
doaj +1 more source
Aspects of the safe use of medicinal products based on medicinal plant materials in COVID-19
Реальная клиническая практика: данные и доказательства, 2022 According to a number of studies, medicinal plants and drugs based on them can be used as inhibitors of various viral infections, including the SARS-CoV-2 virus at different stages of their manifestation and development.
A. A. Taube
doaj +1 more source
Characterisation of the Na, K pump current in atrial cells from patients with and without chronic atrial fibrillation [PDF]
, 2003 <b>Objective:</b> To assess the contribution of the Na, K pump current (<i>I</i><sub>p</sub>) to the action potential duration (APD) and effective refractory period (ERP) in human atrial cells, and to investigate ...
Kane, K.A., Rankin, A.C., Workman, A.J.
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Digitalis and strophanthus—cardiac glycosides [PDF]
Heart, 1998 Digitalis lanata is shown on the 35 dinar Yugoslavian stamp from a set of nine issued in 1957, which includes the deadly nightshade and the meadow saffron. In 1966 Bulgaria also issued a set of flower stamps with the 2 stotinki value showing Digitalis purpurea .
M K, Davies, A, Hollman
openaire +2 more sources
Prospecting endophytic fungal assemblage of Digitalis lanata Ehrh. (foxglove) as a novel source of digoxin: a cardiac glycoside [PDF]
, 2012 Endophytes, the chemical synthesizers inside plants, are the microorganisms having mutualistic relationship with the host plant. They can be used by plants for defense in addition to the production of a wide variety of beneficial bioactive secondary ...
Khalid Zargar +4 more
core +1 more source
Atrial standstill in a horse with cardiac glycoside intoxication [PDF]
, 2012 C
De Clercq, Dominique +4 more
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili +16 more
wiley +1 more source
Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
Spherical oligo-silicic acid SOSA disclosed as possible endogenous digitalis-like factor
Frontiers in Endocrinology, 2015 Na+/K+-ATPase is a membrane ion-transporter protein, specifically inhibited by digitalis glycosides used in cardiac-therapy. The existence in mammals of some endogenous digitalis-like factors (EDLF) as presumed ATPase ligands is generally accepted.
Franz eKerek, Victor A Voicu
doaj +1 more source