Results 51 to 60 of about 47,416 (202)
British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili +16 more
wiley +1 more source
The metabolism of cardiac glycosides: A Study of Some Aspects of the Excretion and Metabolism of Digitalis Glycosides by the Rat. [PDF]
, 1956 The cardiac glycosides, particularly those derived from species of digitalis, have been used extensively in the treatment of cardiac disorders for over two hundred ...
Wright, S. E
core
ESTIMATION OF DIGOXIN AND DIGITOXIN IN DIGITALIS LANATA
, 1958 Digoxin and digitoxin present in extracts of dried leaves of Digitalis lanata have been estimated colorimetrically with xanthydrol after paper chromatographic separation on formamide-impregnated paper, using methyl isobutyl ketone-isopropyl ether ...
P Tantivatana, S E Wright
core +1 more source
Quantitative Analysis of Cardiac Glycosides in Digitalis purpurea and Digitalis lanata with HPLC
, 2013 Cardiac glycosides have a successful track record in the treatment of heart failure. The glycosides digoxin and digitoxin are extracted from the plant species Digitalis purpurea and Digitalis lanata and increase cardiac function and circulation.
Grossens, David
core +1 more source
"Cardiac glycosides"-quo vaditis?-past, present, and future? [PDF]
Naunyn Schmiedebergs Arch PharmacolUp to date, digitalis glycosides, also known as “cardiac glycosides”, are inhibitors of the Na+/K+-ATPase. They have a long-standing history as drugs used in patients suffering from heart failure and atrial fibrillation despite their well-known narrow ...
Fender J +5 more
europepmc +2 more sources
Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
Observations on the Ageing of Digitalis Tinctures
, 1954 Summary and Conclusions It has been confirmed that saponin has no effect on the results of the “overnight” frog method of assay for digitalis.
F Fish, J P Todd
core +1 more source
Evolutionary Applications, Volume 19, Issue 4, April 2026.ABSTRACT Invasive species may exhibit shifts in their gut microbiome in response to novel environments and diet, but this may differ across host species and their time since colonisation. We investigate if site environmental variables and foraged pollen resources differentially shape the gut microbiomes of two bee species with contrasting introduction ...
Sabrina Haque +6 more
wiley +1 more source
Фактори експериментальної еволюції організмів, 2016 Aim. The influence of Agrobacterium rhizogenes-mediated transformation on morphological and biochemical features of D.purpurea. The goal was achieved through the study of the properties of the transformed cell cultures and regenerated plants.
Л. Г. Лёшина +2 more
doaj
Spherical oligo-silicic acid SOSA disclosed as possible endogenous digitalis-like factor
Frontiers in Endocrinology, 2015 Na+/K+-ATPase is a membrane ion-transporter protein, specifically inhibited by digitalis glycosides used in cardiac-therapy. The existence in mammals of some endogenous digitalis-like factors (EDLF) as presumed ATPase ligands is generally accepted.
Franz eKerek, Victor A Voicu
doaj +1 more source