Results 51 to 60 of about 3,015 (202)

A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

Molecules, 2000
A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine
Arturo San Feliciano, Manuel Medarde, Concepción P. Melero   +2 more
doaj   +1 more source

Cardenolides metabolism and genetic transformation of Digitalis. Potentialities and challenges

Biotecnología Vegetal, 2010
Cardenolides are secondary metabolites produced by plants of the genus Digitalis. These are widely used in treatments of congestive heart failure. Failed attempts to obtain suitable cardenolide levels from in vitro culture of Digitalis plants have ...
Yovanny Izquierdo, Naivy Pérez-Alonso, Elio Jiménez   +2 more
doaj  

Exploring the Cancer Therapeutic Potential of Traditional Medicinal Plants by Modulating the Apoptotic Pathway

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Cancer is a versatile disease with a high rate of relapse and mortality. Despite the presence of various treatment modalities, there is a serious need for the development of its management. Phytochemicals, which are abundant in nature, can be turned into novel medications for these types of diseases by optimizing their functions and ...
Mithila Kulkarni, Mohammad Amjad Hussain, Reginald Samson Valdar, Shreya Hebbar, Suparna Laha, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

The metabolism of cardiac glycosides: A Study of Some Aspects of the Excretion and Metabolism of Digitalis Glycosides by the Rat. [PDF]

, 1956
The cardiac glycosides, particularly those derived from species of digitalis, have been used extensively in the treatment of cardiac disorders for over two hundred ...
Wright, S. E
core  

Contemporary medical therapy for heart failure across the ejection fraction spectrum: The OPTIPHARM‐HF registry

European Journal of Heart Failure, Volume 27, Issue 12, Page 2691-2704, December 2025.
Medical therapy use across the left ventricular ejection fraction spectrum in the OPTIPHARM‐HF registry. ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor–neprilysin inhibitor; GDMT, guideline‐directed medical therapy; HF, heart failure; HFmrEF, heart failure with mildly reduced ejection ...
Riccardo M. Inciardi, Maurizio Volterrani, Gianluigi Savarese, Muthiah Vaduganathan, Chiara Oriecuia, Carlo M. Lombardi, Cristina Gussago, Piergiuseppe Agostoni, Pietro Ameri, Giuseppe Armentaro, Chiara Arzilli, Nadia Aspromonte, Andrea Attanasio, Roberto Badagliacca, Lucia Barbieri, Pier Paolo Bocchino, Francesca Bursi, Matteo Cameli, Martino Canonero, Jeness S. Campodonico, Teresa Capovilla, Erberto Carluccio, Stefano Carugo, Vincenzo Castiglione, Dario Catapano, Manlio Cipriani, Michele Correale, Domenico D'Amario, Raffaele De Caterina, Gaetano M. De Ferrari, Emilia D'Elia, Luca Di Odoardo, Michele Emdin, Luigi Falco, Giulia Ferrante, Alessandra Fornaro, Paolo Fornaro, Gionata Guastamiglio, Marco Guazzi, Massimo Iacoviello, Massimo Imazio, Enrico Incaminato, Maria Teresa La Rovere, Sergio Leonardi, Marta Maccallini, Giulia E. Mandoli, Daniele Masarone, Marco Masetti, Alberto Mazzoni, Marta Mazzotta, Marco Merlo, Luigi Moschini, Filippo Novarese, Alberto Palazzuoli, Maria C. Pastore, Giuseppe Patti, Roberto F.E. Pedretti, Stefano Pidello, Massimo F. Piepoli, Giuseppe Pinto, Luciano Potena, Claudia Raineri, Filippo M. Rubbo, Mario Sabatino, Andrea Salzano, Angela Sciacqua, Michele Senni, Paolo Severino, Gianfranco Sinagra, Barbara Sposato, Stefano Taddei, Alessandro Valleggi, Carlo Vignati, Dario Vizza, Claudia Specchia, Giuseppe Rosano, Marco Metra, on behalf of the OPTIPHARM‐HF investigators, Marianna Adamo, Marilisa Ambrosio, Paolo Biagioli, Valeria Borelli, Natale Brunetti, Margherita Calcagnino, Giuseppe Caminiti, Francesco Canonico, Angelo Caporotondi, Velia Cassano, Ali Chraim, Valentina Codazzi, Giuliana Cimino, Francesco Clemenza, Giuditta Cuccuru, Giulia De Lio, Giandomenico Disabato, Marcello Divino, Salvatore D'Isa, Roberta Famiani, Enrica Fede, Letizia Fiòorentino, Alberto Foa', Paolo Fornaro, Noemi Furlotti, Nicolò Gallingani, Alberto Genova, Stefano Ghio, Federico Gobbi, Daniela Grassano, Lucia Guerisoli, Manuela Iseppi, Simona Leone, Ferdinando Loiacono, Valeria Luberto, Rossella Manai, Niccolò Manetti, Lina Manzi, Fabio Marsico, Francesco Maruca, Gabriele Masini, Irene Mattavelli, Ciro Mauro, Alberto Mazzoni, Marta Mazzotta, Pierre Meynet, Valentina Morsella, Giulia Nemola, Martina Niccolai, Savina Nodari, Matteo Pagnesi, Gianpaolo Palmieri, Alberto Panza, Francesca Parisi, Carlo Alberto Pastura, Anna Lisa Picerni, Riccardo Pilia, Ilaria Pirrone, Nicola R. Pugliese, Claudio Puteo, Federica Ramani, Gloria Santangelo, Laura Scelsi, Edoardo Sciatti, Lorenza Sforzini, Giulia Spoto, Davide Stolfo, Roberto Tarantini, Maria Cristina Tavera, Floriana Tortomasi, Eduardo Valente, Giuseppe Varricchione, Enrico Vizzardi, Greta Zagni, Mattia Zampieri   +152 more
wiley   +1 more source

Colored floaters as a manifestation of digoxin toxicity

American Journal of Ophthalmology Case Reports, 2018
Purpose: Since its report in one patient more than 70 years ago, digitalis-induced colored muscae volitantes have not surfaced again in the literature. We report here a case of digoxin induced colored floaters. Observations: An 89-year-old man on 0.25 mg
Lynn Shi, Linus D. Sun, Jeffrey G. Odel
doaj   +1 more source

Integrating Nature Into Oncology: Enhancing Hematological Malignancies Therapies With Natural Medicine

Cancer Medicine, Volume 14, Issue 21, November 2025.
ABSTRACT Hematological malignancies are complex clonal disorders that pose a significant threat to human health. Current treatment modalities, including radiotherapy, chemotherapy, immunotherapy, and bone marrow transplantation, have demonstrated efficacy but are often limited by side effects, drug resistance, and suboptimal cure rates.
Yaoyao Tian, Baoyi Ni, Dandan Cai, Jia Wang, Jilai Zhou, Mingqian Song, Xi Zhang, Jiakang Jiang   +7 more
wiley   +1 more source

Effects of digitalis on cell biochemistry: Sodium pump inhibition

, 1985
It is now generally agreed that Na+−K+adenosine triphosphatase (ATPase), a transport enzyme derived from the sarcolemmal sodium pump, is the primary site at which digitalis exerts its effects on the myocardial cell.
Katz, Arnold M., Arnold M. Katz
core   +1 more source

Growth and Photosynthetic Characteristics of Two Strawberry Cultivars in Response to Furostanol Glycosides Treatments

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2013
Furostanol glycosides represent a large group of steroid compounds of plant origin with a broad spectrum of biological activities (anabolic, antioxidant, anti-fungal and nematicidal).
Raluca Petronela CĂULEŢ, Aliona MORARIU, Dorina IUREA, Gică GRĂDINARIU   +3 more
doaj   +1 more source

Progestogens and androgens influence root morphology of angiosperms in a brassinosteroid‐independent manner

The Plant Journal, Volume 123, Issue 5, September 2025.
Significance Statement Plants produce progesterone and androgens, which alter root morphology in A. thaliana and 60% of tested angiosperms. Brassinosteroids seem uninvolved. Understanding the mechanism is like navigating an unknown city—exemplarily Dittelbrunn (a small village in Bavaria)—where the expected shortcut (interaction with brassinosteroids ...
Karl Ludwig Körber, Sudip Paul, Jana Oklestkova, Emanuel Barth, Felix Feistel, Henk Oppermann, Ceren Oktay, Maja Dorfner, Miroslav Strnad, Jennifer Munkert, Alexandra C. U. Furch, Jan Klein   +11 more
wiley   +1 more source