Results 61 to 70 of about 3,015 (202)

An examination of Digitalis purpurea and its glycosides in relation to the loss of activity on storage [PDF]

open access: yes, 1955
1. Tinctures prepared from either dried or stabilised digitalis leaf sure unstable on storage, losing up to 60 per cent, of initial potency as determined by the 18-hour method of assay on frogs. 2.
Fish, Francis
core  

HFrEF pharmacological treatment: digitalis glycosides

open access: yes, 2018
About 25 years ago, a series of trials suggested that withdrawal of digoxin from patients with heart failure who were stable, had mild symptoms, a reduced left ventricular ejection fraction, and in sinus rhythm could lead to worsening symptoms ...
John G. F Cleland, Yura Mareev
core   +1 more source

Secondary Metabolites from the Leaves of

open access: yesNatural Product Communications, 2017
A new phenylethanoid glycoside, named digiviridifloroside ( 1 ), was isolated from the leaves of Digitalis viridiflora Lindley along with a known phenylethanoid glycoside calceolarioside A ( 2 ), two flavonoid glycosides, scutellarein 7- O -β-D ...
Hasan Kırmızıbekmez   +4 more
doaj   +1 more source

Landscape‐Wide Metabarcoding Shows Interactions Among the Gut Microbiome and Pollen Diversity in the Invasive Bumblebee, Bombus terrestris

open access: yesEcology and Evolution, Volume 15, Issue 7, July 2025.
The study examines how environmental factors and dietary diversity influence the gut microbiome of the invasive European buff‐tailed bumblebee (Bombus terrestris) in Tasmania. We found that gut bacterial composition and diversity were significantly affected by annual precipitation, pasture percentage, temperature and interactions between pollen ...
Sabrina Haque   +6 more
wiley   +1 more source

Avaliação dos efeitos citotóxicos de cardenolídeos em células tumorais [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaOs cardenolídeos são metabólitos secundários encontrados na natureza e assim denominados em razão de sua ação inibitória na
Carvalho, Annelise de
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DIGitoxin to Improve ouTcomes in patients with advanced chronic Heart Failure (DIGIT‐HF): Baseline characteristics compared to recent randomized controlled heart failure trials

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 7, Page 1224-1233, July 2025.
Effects of digitoxin compared to placebo on efficacy and safety in patients with heart failure and reduced ejection fraction (HFrEF). Primary endpoint: time to all‐cause death and first hospitalization for worsening heart failure (whatever occurs first). ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin
Udo Bavendiek   +144 more
wiley   +1 more source

Steroidal Glycosides of Cordyline australis

open access: yes, 2006
The n-butanol extract of aerial parts of Cordyline australis demonstrated antifungal activity. n-Butanol and chloroform extracts of dried or fresh leaves of C. australis afforded a steroidal glycoside, which was identified as 5α-spirost-25(27)-en-3β-ol 3-
Korkashvili, Tamar
core  

Comprehensive transcriptome analysis reveals novel genes involved in cardiac glycoside biosynthesis and mlncRNAs associated with secondary metabolism and stress response in Digitalis purpurea

open access: yesBMC Genomics, 2012
Background Digitalis purpurea is an important ornamental and medicinal plant. There is considerable interest in exploring its transcriptome. Results Through high-throughput 454 sequencing and subsequent assembly, we obtained 23532 genes, of which 15626 ...
Wu Bin   +7 more
doaj   +1 more source

Apteranthes tuberculata's Antidiabetic Potential: Exploring Phytochemicals, Screening Antioxidant Activity, and Validating DPP‐4 Inhibition Using In Vitro and In Silico Approaches

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
Metabolomics revealed 24 major compounds, mainly glycosides, flavonoids, and triterpenes. Antidiabetic compounds Kaempferol‐7‐O‐rutinoside and Kaempferol‐3‐O‐rutinoside‐7‐O‐glucoside show maximum inhibiting activity for DPP4 protein (in vitro and in silico). Out of 24 compounds, 5 demonstrate no PAINS and break alerts.
Ilham Khan   +7 more
wiley   +1 more source

Quantitative Analysis of Cardiac Glycosides in Digitalis purpurea and Digitalis lanata with HPLC

open access: yes, 2013
Cardiac glycosides have a successful track record in the treatment of heart failure. The glycosides digoxin and digitoxin are extracted from the plant species Digitalis purpurea and Digitalis lanata and increase cardiac function and circulation.
Grossens, David
core  

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