Results 71 to 80 of about 5,715 (204)

Integrating Nature Into Oncology: Enhancing Hematological Malignancies Therapies With Natural Medicine

open access: yesCancer Medicine, Volume 14, Issue 21, November 2025.
ABSTRACT Hematological malignancies are complex clonal disorders that pose a significant threat to human health. Current treatment modalities, including radiotherapy, chemotherapy, immunotherapy, and bone marrow transplantation, have demonstrated efficacy but are often limited by side effects, drug resistance, and suboptimal cure rates.
Yaoyao Tian   +7 more
wiley   +1 more source

Secondary Metabolites from the Leaves of

open access: yesNatural Product Communications, 2017
A new phenylethanoid glycoside, named digiviridifloroside ( 1 ), was isolated from the leaves of Digitalis viridiflora Lindley along with a known phenylethanoid glycoside calceolarioside A ( 2 ), two flavonoid glycosides, scutellarein 7- O -β-D ...
Hasan Kırmızıbekmez   +4 more
doaj   +1 more source

Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]

open access: yes, 2008
Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J.   +4 more
core  

Progestogens and androgens influence root morphology of angiosperms in a brassinosteroid‐independent manner

open access: yesThe Plant Journal, Volume 123, Issue 5, September 2025.
Significance Statement Plants produce progesterone and androgens, which alter root morphology in A. thaliana and 60% of tested angiosperms. Brassinosteroids seem uninvolved. Understanding the mechanism is like navigating an unknown city—exemplarily Dittelbrunn (a small village in Bavaria)—where the expected shortcut (interaction with brassinosteroids ...
Karl Ludwig Körber   +11 more
wiley   +1 more source

Comprehensive transcriptome analysis reveals novel genes involved in cardiac glycoside biosynthesis and mlncRNAs associated with secondary metabolism and stress response in Digitalis purpurea

open access: yesBMC Genomics, 2012
Background Digitalis purpurea is an important ornamental and medicinal plant. There is considerable interest in exploring its transcriptome. Results Through high-throughput 454 sequencing and subsequent assembly, we obtained 23532 genes, of which 15626 ...
Wu Bin   +7 more
doaj   +1 more source

Chemical Constituents of Wild Onion Urginea Indica Kunth Liliaceae [PDF]

open access: yes, 2013
Wild Onion Urginea indica provide health promoting phytochemicals, as well as nutrients. Onions are bitter to taste, they contains plenty of raphides in bulbs which acts as defensive mechanism.
Shiva Kameshwari, M.N.
core  

Landscape‐Wide Metabarcoding Shows Interactions Among the Gut Microbiome and Pollen Diversity in the Invasive Bumblebee, Bombus terrestris

open access: yesEcology and Evolution, Volume 15, Issue 7, July 2025.
The study examines how environmental factors and dietary diversity influence the gut microbiome of the invasive European buff‐tailed bumblebee (Bombus terrestris) in Tasmania. We found that gut bacterial composition and diversity were significantly affected by annual precipitation, pasture percentage, temperature and interactions between pollen ...
Sabrina Haque   +6 more
wiley   +1 more source

Characterisation of Na/K-ATPase, its isoforms, and the inotropic response to ouabain in isolated failing human hearts [PDF]

open access: yes, 2017
Objective: The aim was to determine whether failing human hearts have increased sensitivity to the inotropic and toxic effects of ouabain, and to examine alterations in Na/K-ATPase that might explain the observed higher ouabain sensitivity.
Gradoux, Nathalie   +7 more
core  

Digitálicos: los resultados del DIG en el siglo XXI [PDF]

open access: yes, 2010
After the report that there was no statistical significance in the general mortality of the DIG study, the indication of digoxin in the treatment regimens for congestive heart failure (CHF) drastically decreased.
Helber, Izo, Tucci, Paulo José Ferreira
core   +4 more sources

DIGitoxin to Improve ouTcomes in patients with advanced chronic Heart Failure (DIGIT‐HF): Baseline characteristics compared to recent randomized controlled heart failure trials

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 7, Page 1224-1233, July 2025.
Effects of digitoxin compared to placebo on efficacy and safety in patients with heart failure and reduced ejection fraction (HFrEF). Primary endpoint: time to all‐cause death and first hospitalization for worsening heart failure (whatever occurs first). ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin
Udo Bavendiek   +144 more
wiley   +1 more source

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