Results 81 to 90 of about 5,715 (204)

Effect of salicylic acid and some plant extracts on growth and stimulation of cardiac glycosidic compounds of Digitalis lanata in vitro

Journal of Medicinal and Industrial Plant Sciences
The research aimed to investigate the effect of salicylic acid, and some plant extracts some factors on growth indicators and stimulating cardiac glycosides in digitalis leaves, in the Plant Tissue Culture Laboratory - College of Agricultural Engineering
Lamiaa K J Al-Amery, Zainab J. Al-Mousawi   +1 more
doaj   +1 more source

Medicinal Plants: A Public Resource for Metabolomics and Hypothesis Development

Metabolites, 2012
Specialized compounds from photosynthetic organisms serve as rich resources for drug development. From aspirin to atropine, plant-derived natural products have had a profound impact on human health.
Eve Syrkin Wurtele, Joe Chappell, A. Daniel Jones, Mary Dawn Celiz, Nick Ransom, Manhoi Hur, Ludmila Rizshsky, Philip Dixon, Jia Liu, Mark P. Widrlechner, Basil J. Nikolau   +10 more
doaj   +1 more source

Apteranthes tuberculata's Antidiabetic Potential: Exploring Phytochemicals, Screening Antioxidant Activity, and Validating DPP‐4 Inhibition Using In Vitro and In Silico Approaches

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Metabolomics revealed 24 major compounds, mainly glycosides, flavonoids, and triterpenes. Antidiabetic compounds Kaempferol‐7‐O‐rutinoside and Kaempferol‐3‐O‐rutinoside‐7‐O‐glucoside show maximum inhibiting activity for DPP4 protein (in vitro and in silico). Out of 24 compounds, 5 demonstrate no PAINS and break alerts.
Ilham Khan, Shabana Bibi, Junaid Shehzad, Zarqa Riaz, Muhammad Saad Khan, Mansour Ghorbanpour, Murtaza Hasan, Ghazala Mustafa   +7 more
wiley   +1 more source

Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm [PDF]

, 2016
Many conditions culminate in heart failure (HF), a multi-organ systemic syndrome with an intrinsically poor prognosis. Pharmacotherapeutic agents that correct neurohormonal dysregulation and haemodynamic instability have occupied the forefront of ...
Abozguia, AIRE Study Group, Alexander, Alexander, Alexander, Alexander, Ashrafian, Bailey, Bailey, Basu, Beadle, Braunwald, Brown, Burgoyne, Chaitman, Chatterjee, Chung, CIBIS-II Study Group, Cleland, Clerc, Cohn, Cohn, Cohn, CONSENSUS Trial Study Group, Conway, Cook, Dai, Digitalis Investigation Group, Doenst, Dzau, Dzau, Faris, Flather, Follath, Foster, Fox, Fox, Fragasso, Furberg, Gheorghiade, Gladwin, Goffart, Granger, Greenberg, Guazzi, Guazzi, Heymans, Hobbs, Holubarsch, Horowitz, Horowitz, Kantor, Kapil, Kato, Kennedy, Kennedy, Kostis, Larsen, Lee, Lopaschuk, Luiken, Lundberg, Maher, Maier, Mancini, Mann, Mann, Massie, Mccormack, Mcdowell, Mcmurray, Mcmurray, Merit-Hf Study Group, Munzel, Munzel, Neglia, Neubauer, Ormerod, Packer, Packer, Paul, Pawson, Pfeffer, Pfeffer, Pitt, Pitt, Rathore, Rauchhaus, Redfield, Rona, Sack, Sarraf, Schmidt-Schweda, Schrauwen, Schwarz, Shah, Shah, Siddiqi, Singh, SOLVD Investigators, Stanley, Swedberg, Szwed, Taylor, Teerlink, Tilemann, Torre-Amione, Totzeck, Turcani, Unger, Van Der Vusse, Van Faassen, Vardeny, Webb, Yin, Yusuf, Zamani, Zannad, Zannad, Zhang   +119 more
core   +1 more source

Toxic plants and companion animals. [PDF]

, 2009
Poisoning by substances of plant origin is unusual in both dogs and cats, yet it is possible; as many veterinarians do not know which plants can contain toxic active principles, the possibility of intoxication by ornamental plants commonly used to ...
SEVERINO, LORELLA
core   +1 more source

Carbohydrate Synthesis is Entering the Data‐Driven Digital Era

Chemistry – A European Journal, Volume 31, Issue 27, May 14, 2025.
The outcome of glycosylations, essential for glycochemistry, is difficult to predict due to its intricate mechanism and the influence of protective groups. Recent advances illustrate that integrating digital tools like automation, computational modelling, and data management drives progress in the carbohydrate synthesis field.
Eric T. Sletten, Jakob B. Wolf, José Danglad‐Flores, Peter H. Seeberger   +3 more
wiley   +1 more source

Sodium ion channel mutations in glioblastoma patients correlate with shorter survival [PDF]

, 2011
Background Glioblastoma Multiforme (GBM) is the most common and invasive astrocytic tumor associated with dismal prognosis. Treatment for GBM patients has advanced, but the median survival remains a meager 15 months.
Avadhut D Joshi, D Parsons, Victor E Velculescu, Gregory J Riggins   +3 more
core   +2 more sources

Cardiac glycosides use and the risk and mortality of cancer; systematic review and meta-analysis of observational studies.

PLoS ONE, 2017
BackgroundCardiac glycosides (CGs) including digitalis, digoxin and digitoxin are used in the treatment of congestive heart failure and atrial fibrillation.
Mohamed Hosny Osman, Eman Farrag, Mai Selim, Mohamed Samy Osman, Arwa Hasanine, Azza Selim   +5 more
doaj   +1 more source

The major changes in medical practice in the 20th century [PDF]

, 2000
One could truly say that there were more advances in medicine in the last 60 years than there had been in the previous 500 years. Indeed the medical breakthroughs of the last 50 years have probably saved more lives than those of any epoch since medicine ...
Fenech, Frederick F.
core  

Associations between comorbidities, their treatment and survival in patients with interstitial lung diseases – a claims data analysis [PDF]

, 2018
Background: Interstitial lung diseases (ILDs) are associated with a high burden of disease. However, data on the prognostic impact of comorbidities and comorbidity-related pharmaceutical treatments in patients with various ILDs remain sparse. Methods:
Kreuter, Michael, Polke, Markus, Schwarzkopf, Larissa, Waelscher, Julia, Witt, Sabine   +4 more
core   +1 more source