Results 71 to 80 of about 6,589 (233)

Effect of salicylic acid and some plant extracts on growth and stimulation of cardiac glycosidic compounds of Digitalis lanata in vitro

open access: yesJournal of Medicinal and Industrial Plant Sciences
The research aimed to investigate the effect of salicylic acid, and some plant extracts some factors on growth indicators and stimulating cardiac glycosides in digitalis leaves, in the Plant Tissue Culture Laboratory - College of Agricultural Engineering
Lamiaa K J Al-Amery   +1 more
doaj   +1 more source

Mechanisms contributing to the cardiac inotropic effect of Na pump inhibition and reduction of extracellular Na. [PDF]

open access: yes, 1987
Reduction of the transsarcolemmal [Na] gradient in rabbit cardiac muscle leads to an increase in the force of contraction. This has frequently been attributed to alteration of Ca movements via the sarcolemmal Na/Ca exchange system.
Bers, DM
core  

The effect of down‐titration and discontinuation of heart failure pharmacotherapy in older people: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 1, Page 23-37, January 2025.
The aim of this study was to investigate whether interventions to discontinue or down‐titrate heart failure (HF) pharmacotherapy are feasible and associated with risks in older people. A systematic review and meta‐analysis were conducted according to PRISMA 2020 guidelines. Electronic databases were searched from inception to 8 March 2023.
Mai H. Duong   +6 more
wiley   +1 more source

Deciphering the Molecular Pathways: How Polygonatum sibiricum Alleviates Myocardial Ischemia

open access: yesJournal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Herbal medicine, like Polygonatum sibiricum, is gaining attention for its potential in treating myocardial ischemia. Comprehensive research on its molecular interplay is essential for its development as a therapeutic agent. The aim is to investigate the molecular mechanisms by which Polygonatum sibiricum ameliorates myocardial ischemia.
Zhenzhong Zhu   +8 more
wiley   +1 more source

Evaluation of chromosome abberations induced by digoxin in Chinese hamster ovary cells [PDF]

open access: yes, 2013
Digoxin is a cardiac glycoside that has been reported to inhibit growth of multiple tumor cell types in vitro. The present study was assessing the cytogenetic effects of this drug on Chinese Hamster Ovary (CHO) cells.
Saadat, Iraj   +2 more
core  

Therapeutic Promises of Bioactive Linarin, a Glycosylated Flavonoid: A Comprehensive Review With Mechanistic Insight

open access: yesJournal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Linarin, a flavonoid glycoside found in the Asteraceae, Lamiaceae, and Scrophulariaceae families, shows diverse therapeutic benefits in laboratory studies. This study aims to evaluate the pharmacological effects of linarin through clinical and preclinical experiments, investigating its mechanisms against different diseases.
Faysal Mollah   +9 more
wiley   +1 more source

Cardiac glycosides use and the risk and mortality of cancer; systematic review and meta-analysis of observational studies.

open access: yesPLoS ONE, 2017
BackgroundCardiac glycosides (CGs) including digitalis, digoxin and digitoxin are used in the treatment of congestive heart failure and atrial fibrillation.
Mohamed Hosny Osman   +5 more
doaj   +1 more source

The major changes in medical practice in the 20th century [PDF]

open access: yes, 2000
One could truly say that there were more advances in medicine in the last 60 years than there had been in the previous 500 years. Indeed the medical breakthroughs of the last 50 years have probably saved more lives than those of any epoch since medicine ...
Fenech, Frederick F.
core  

Digoxin-induced retinal degeneration depends on rhodopsin [PDF]

open access: yes, 2017
Na,K-ATPases are energy consuming ion pumps that are required for maintaining ion homeostasis in most cells. In the retina, Na,K-ATPases are especially important to sustain the dark current in photoreceptor cells needed for rapid hyperpolarization of ...
Landfried, Britta   +6 more
core   +1 more source

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