Results 71 to 80 of about 256 (152)
Saponins enhance exon skipping of 2′-O-methyl phosphorothioate oligonucleotide in vitro and in vivo
Drug Design, Development and Therapy, 2018 Mingxing Wang, Bo Wu, Sapana N Shah, Peijuan Lu, Qilong Lu McColl-Lockwood Laboratory for Muscular Dystrophy Research, Department of Neurology, Cannon Research Center, Carolinas Medical Center, Charlotte, NC 28203, USA Background: Antisense ...
Wang M, Wu B, Shah SN, Lu P, Lu Q
doaj
Sterol synthesis in intestinal villi and crypt cells of rats and guinea pigs
Journal of Lipid Research, 1977 The villi of the small intestine of rats and guinea pigs have been demonstrated to be capable of as rapid synthesis of sterols as the crypt cell fractions.
H Muroya, H S Sodhi, R G Gould
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Molecular Microbiology, EarlyView.The mitochondrial membrane‐shaping machinery MICOS is assembled surprisingly early during the life cycle of Trypanosoma brucei, before the mitochondrion acquires its mature architecture or full respiratory capacity. Our study also identifies two previously uncharacterized proteins associated with MICOS, providing new insight into the early organization
Michala Boudová +5 more
wiley +1 more source
Daily Heat Stress Induces Donor‐Side Limitation of PSI Via Downregulation of the Cyt b6f Complex
Plant, Cell &Environment, EarlyView.ABSTRACT The rapidly warming climate is driving increasingly frequent and intense heat waves worldwide, posing major challenges to plant metabolism and growth. Despite the central role of photosynthesis in plant growth, the effects of prolonged heat stress on the primary reactions of photosynthesis remain poorly understood.
Laura Laihonen +5 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova +6 more
wiley +1 more source
Phosphomevalonate kinase is a cytosolic protein in humans
Journal of Lipid Research, 2004 In the past decade, a predominant peroxisomal localization has been reported for several enzymes functioning in the presqualene segment of the cholesterol/isoprenoid biosynthesis pathway.
Sietske Hogenboom +5 more
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The Journal of Physiology, EarlyView.Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin +7 more
wiley +1 more source
THE INHIBITORY EFFECT OF DEHYDROEPIANDROSTERONE ON THE ACTIVITY AND ISOENZYME PATTERNS OF LIVER GLUCOSE 6-PHOSPHATE DEHYDROGENASE DURING DIFFERENT STAGES OF GROWTH [PDF]
Journal of Sciences, Islamic Republic of Iran, 1990 The effect of dehydroepiandrosterone (DHEA) on the activity and isoenzyme patterns of liver glucose 6- phosphate dehydrogenase (G6PD) was investigated in rats during different stages of growth.
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Zur Kenntniss des Digitonins [PDF]
Berichte der deutschen chemischen Gesellschaft, 1891 n ...
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WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization
The FASEB Journal, Volume 40, Issue 16, 31 August 2026.We identify WAVE2 as a key regulator of clustered gene expression via heterochromatin organization. Loss of WAVE2 leads to the expression of Pcdhα genes shifting from stochastic to ubiquitous isoforms, concurrent with altered promoter accessibility. REST/NRSF similarly regulates Pcdhα gene expression by organizing heterochromatin, indicating distinct ...
Leyang Wang +4 more
wiley +1 more source