Results 61 to 70 of about 10,900 (273)

Consequences of toxic secondary compounds in nectar for mutualist bees and antagonist butterflies [PDF]

, 2016
Attraction of mutualists and defense against antagonists are critical challenges for most organisms and can be especially acute for plants with pollinating and non?pollinating flower visitors.
Agrawal, Anurag A., Jones, Patricia L.
core   +2 more sources

Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding

Annals of the American Thoracic Society, 2017
Rationale: Cystic fibrosis (CF) lung disease progresses by a combination of airway inflammation, bacterial colonization, and infection. Airway inflammation is predominantly neutrophilic and complicates airway clearance therapies through cellular debris ...
P. Zeitlin, M. Diener-West, K. Callahan, Seakwoo Lee, C. Talbot, B. Pollard, M. Boyle, N. Lechtzin   +7 more
semanticscholar   +1 more source

A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry

ESC Heart Failure, EarlyView.
The H2‐Registry: overview, first results and outlook. Abstract Aims Heart failure (HF) is a highly prevalent condition affecting 1–3% of the adult population in Europe. Despite landmark improvements in HF care over the last two decades, hospitalization and mortality rates remain relatively high.
Johannes Leiner, Sebastian König, Anne Nitsche, Sven Hohenstein, Jana Nagel, Melchior Seyfarth, Henning Baberg, Alexander Lauten, Hans Neuser, Alexander Staudt, Jürgen Tebbenjohanns, René Andrié, Michael Niehaus, Markus W. Ferrari, Ralf Kuhlen, Andreas Bollmann   +15 more
wiley   +1 more source

In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis

Parasite, 2021
Current treatments of visceral leishmaniasis face limitations due to drug side effects and/or high cost, along with the emergence of parasite resistance. Novel and low-cost antileishmanial agents are therefore required.
Freitas Camila S., Lage Daniela P., Oliveira-da-Silva João A., Costa Rafaella R., Mendonça Débora V.C., Martins Vívian T., Reis Thiago A.R., Antinarelli Luciana M.R., Machado Amanda S., Tavares Grasiele S.V., Ramos Fernanda F., Brito Rory C.F., Ludolf Fernanda, Chávez-Fumagalli Miguel A., Roatt Bruno M., Ramos Gabriela S., Munkert Jennifer, Ottoni Flaviano M., Campana Priscilla R.V., Duarte Mariana C., Gonçalves Denise U., Coimbra Elaine S., Braga Fernão C., Pádua Rodrigo M., Coelho Eduardo A.F.   +24 more
doaj   +1 more source

rMAPS: RNA map analysis and plotting server for alternative exon regulation. [PDF]

, 2016
RNA-binding proteins (RBPs) play a critical role in the regulation of alternative splicing (AS), a prevalent mechanism for generating transcriptomic and proteomic diversity in eukaryotic cells.
Jung, Sungbo, Park, Juw Won, Rouchka, Eric C, Tseng, Yu-Ting, Xing, Yi   +4 more
core   +2 more sources

Exploring the Potential of Tsuruazuki Bean as a Functional Food to Curb Obesity Using Human Amniotic Epithelial Cells and 3T3‐L1 Preadipocytes

Food Frontiers, EarlyView.
Obesity is a global health problem that requires research and regulatory attention. This research aims to investigate transcriptome‐wide changes induced by Vigna umbellata (Tsuruazuki) using a stem cell‐based tool and preadipocytes to explore its untapped potential as a functional food for anti‐obesity applications.
Elda Nurafnie Ibnu Rasid, Farhana Ferdousi, Kazunori Sasaki, Kyoko Toda, Shinya Takahashi, Mari Maeda‐Yamamoto, Hiroko Isoda   +6 more
wiley   +1 more source

Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity

Foods, 2021
Cardiac glycosides (CGs) represent a group of sundry compounds of natural origin. Most CGs are potent inhibitors of Na+/K+-ATPase, and some are routinely utilized in the treatment of various cardiac conditions. Biological activities of other lesser known
Silvie Rimpelová, Tomáš Zimmermann, Pavel B. Drašar, Bohumil Dolenský, Jiří Bejček, Eva Kmoníčková, Petra Cihlářová, Soňa Gurská, Lucie Kuklíková, Marián Hajdůch, Tomáš Ruml, Lubomír Opletal, Petr Džubák, Michal Jurášek   +13 more
doaj   +1 more source

Digoxin Inhibits Retinoblastoma through Suppressing a Non-canonical TGFβ Signaling Pathway. [PDF]

, 2016
Aims: Retinoblastoma is a childhood ocular tumor rapidly developing from the immature cells of the retina due to loss of functional retinoblastoma protein.
Akbari, Abolfazl., Ghassemi, Fariba., Heidari, Mansour., Karkhaneh, Reza., Mobini, Gholam Reza., Mohebbi, Masoumeh., Sadeghi, Abdolrahim., Shahrzad Kavakani, Mahshid., Sheikhzade, Maryam.   +8 more
core   +1 more source

The Therapeutic Effects of Digitoxine [PDF]

The American Journal of the Medical Sciences, 1894
n ...
openaire   +2 more sources

Screening for cardiac glycosides in Schizobasis intricata [PDF]

, 1995
Traditional herbalists in Natal use Schizobasis intricata (Bak.) Bak, as a substitute for Bowiea volubilis Harv. ex Hook. This may be due to morphological confusion of the two species or they may elicit a similar biological response.
Jäger, Anna K., van Staden, J.
core   +1 more source