Results 81 to 90 of about 43,790 (236)

Dicloxacillin and Flucloxacillin Inhibit Hepatic Uptake Transporters—In Vitro Investigations and Physiologically Based Pharmacokinetic Modeling

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Dicloxacillin and flucloxacillin are β‐lactamase‐resistant penicillin antibiotics that have been in clinical use for over 50 years. While both antibiotics are known to induce cytochrome P450 enzymes, there is limited information available regarding their interactions with drug transporters.
Noora Sjöstedt   +7 more
wiley   +1 more source

780 Treatment of life-threatening digoxin toxicity with digoxin immune fab antibody: findings from the UK DigiFab®patient registry [PDF]

open access: bronze, 2022
Emma Thomas   +6 more
openalex   +1 more source

Falling into complexity: A case of digitalis-induced fall, trauma, symptomatic bradycardia, and syncope

open access: yesJournal of Family Medicine and Primary Care
Digoxin, a cardiac glycoside, functions by inhibiting the sodium potassium ATPase pump. It’s crucial to note that digoxin has a very narrow therapeutic range. Its serum level vary due to changes in body weight, age, renal function, hepatic impairment and
Rajathadri H. Ravikumar   +3 more
doaj   +1 more source

Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug–drug interaction study

open access: yesClinical Pharmacology: Advances and Applications, 2014
Debra J Tompson,1 Christopher S Crean,2 Mauro Buraglio,1 Thangam Arumugham3 1Clinical Pharmacology Modelling and Simulation, GlaxoSmithKline, Stevenage, Hertfordshire, UK; 2Clinical Pharmacology and Pharmacokinetics, Valeant Pharmaceuticals North America,
Tompson DJ   +3 more
doaj  

Digoxin measurements in general practice. [PDF]

open access: bronze, 1977
Holt Dw, JD Williamson, GN Volans
openalex   +1 more source

Severe Digoxin Toxicity in a Child Managed with Cholestyramine. A Case Report

open access: yesSaudi Journal of Emergency Medicine
Digoxin toxicity is a common problem in clinical practice because its therapeutic window is relatively narrow (from 0.5 to 2 ng/ml). The toxic effects occur at concentrations > 2.8 ng/ml and are mainly related to disturbances of cardiac function and ...
Suman Noorani   +3 more
doaj   +1 more source

Effect of green tea catechins on the pharmacokinetics of digoxin in humans

open access: yesDrug Design, Development and Therapy, 2018
Tae-Eun Kim,1 Kwang-Hee Shin,2 Jeong-Eun Park,2 Min-Gul Kim,3 Yeo-Min Yun,4 Dong-Hee Choi,5 Kyoung Ja Kwon,5 Jongmin Lee6 1Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Republic of Korea; 2Department of Pharmacotherapy ...
Kim TE   +7 more
doaj  

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