Results 91 to 100 of about 23,186 (181)

Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis. [PDF]

Acta Pharm Sin B, 2023
Shao N, Ma X, Zhang YY, Yang D, Ma M, Tang GL.   +5 more
europepmc   +1 more source

Exploring antibiotic resistance in diverse homologs of the dihydrofolate reductase protein family through broad mutational scanning. [PDF]

Sci Adv
Romanowicz KJ, Resnick C, Hinton SR, Plesa C.   +3 more
europepmc   +1 more source

Metabolic inhibitor screening identifies dihydrofolate reductase as an inducer of the tumor immune escape mediator CD24. [PDF]

Immunomedicine, 2022
Boese AC, Hwang JS, Young I, Malin CM, Avalos V, Kang J, Kang S.   +6 more
europepmc   +1 more source

Methotrexate binding to dihydrofolate reductase [PDF]

Nature, 1980
G C, Roberts, J, Feeney, B, Birdsall, P, Charlton, D, Young   +4 more
openaire   +2 more sources

Identification of potential inhibitors of dihydrofolate reductase (DHFR) through blocking the folate biosynthetic pathway of <i>Mycobacterium tuberculosis</i> utilizing structure-based virtual screening. [PDF]

RSC Adv
Halder SK, Sultana A, Ahmad I, Rafi MO, Sultana I, Elma F, Ananna IJ, Patel H, Himel MK, Shil A.   +9 more
europepmc   +1 more source

Increased NOX2 expression in astrocytes leads to eNOS uncoupling through dihydrofolate reductase in endothelial cells after subarachnoid hemorrhage. [PDF]

Front Mol Neurosci, 2023
Miao SH, Gao SQ, Li HX, Zhuang YS, Wang X, Li T, Gao CC, Han YL, Qiu JY, Zhou ML.   +9 more
europepmc   +1 more source

Statistical Coupling Analysis Predicts Correlated Motions in Dihydrofolate Reductase. [PDF]

J Phys Chem B
Kalmer TL, Ancajas CMF, Cohen CI, McDaniel JM, Oyedele AS, Thirman HL, Walker AS.   +6 more
europepmc   +1 more source

Comparison of the Role of Protein Dynamics in Catalysis by Dihydrofolate Reductase from E. coli and H. sapiens. [PDF]

J Phys Chem B, 2022
Andrews BA, Dyer RB.
europepmc   +1 more source

Resistance of Wolbachia to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales. [PDF]

Insects
Fallon AM.
europepmc   +1 more source

Palbociclib regulates the expression of dihydrofolate reductase and the cell cycle to inhibit t (11;14) multiple myeloma. [PDF]

Ann Transl Med, 2022
Wang Y, Wang H, Wang X.
europepmc   +1 more source