Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant [PDF]
, 2007 Natércia Fernandes +3 more
openalex +1 more source
NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions [PDF]
, 2011 J. Feeney +5 more
openalex +1 more source
An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase [PDF]
, 2022 Lois Kwane Kyei +4 more
openalex +1 more source
Electron Transfer-oxy Radical Mechanism for Anti-cancer Agents: 9-anilinoacridines [PDF]
, 1987 A possible mode of action involving electron transfer is advanced for the 9- anilinoacridines. The mechanism entails formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R. +2 more
core +1 more source
Kinetic analysis of the mechanism of Escherichia coli dihydrofolate reductase.
, 1987 Michael H. Penner, Carl Frieden
openalex +1 more source
Supplementary Figure 1 from MDM2 Regulates Dihydrofolate Reductase Activity through Monoubiquitination [PDF]
, 2023 Maria Maguire +7 more
openalex +1 more source
Import of apocytochrome c into the mitochondrial intermembrane space along a cytochrome c1 sorting pathway [PDF]
, 1990 The question of whether cytochrome c could be functionally sorted to the mitochondrial intermembrane space along a "conservative sorting" pathway was investigated using a fusion protein termed pLc1-c. pLc1-c contains 3-fold targeting information, namely,
Neupert, Walter +3 more
core
Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry. [PDF]
Protein Sci, 2023 Kazan IC, Mills JH, Ozkan SB.
europepmc +1 more source
Sequence of the dihydrofolate reductase-thymidylate synthase (DHFR-TS) gene ofLeishmania amazonensis
, 1990 Kimberlyn Nelson +3 more
openalex +2 more sources