Results 121 to 130 of about 23,665 (170)

Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis. [PDF]

Acta Crystallogr F Struct Biol Commun, 2022
Porter I, Neal T, Walker Z, Hayes D, Fowler K, Billups N, Rhoades A, Smith C, Smith K, Staker BL, Dranow DM, Mayclin SJ, Subramanian S, Edwards TE, Myler PJ, Asojo OA.   +15 more
europepmc   +1 more source

Cymoxanil disrupts RNA synthesis through inhibiting the activity of dihydrofolate reductase. [PDF]

Sci Rep
Kazmirchuk TDD, Burnside DJ, Wang J, Jagadeesan SK, Al-Gafari M, Silva E, Potter T, Bradbury-Jost C, Ramessur NB, Ellis B, Takallou S, Hajikarimlou M, Moteshareie H, Said KB, Samanfar B, Fletcher E, Golshani A.   +16 more
europepmc   +1 more source

Correction: Silva, P.J. Computational Development of Inhibitors of Plasmid-Borne Bacterial Dihydrofolate Reductase. Antibiotics 2022, 11, 779. [PDF]

Antibiotics (Basel)
Silva PJ.
europepmc   +1 more source

Design, synthesis, in vitro and in silico studies of novel piperidine derived thiosemicarbazones as inhibitors of dihydrofolate reductase. [PDF]

Sci Rep
Aftab H, Ullah S, Khan A, Al-Rashida M, Islam T, Dahlous KA, Mohammad S, Kashtoh H, Al-Harrasi A, Shafiq Z.   +9 more
europepmc   +1 more source

Benzamide Trimethoprim Derivatives as Human Dihydrofolate Reductase Inhibitors-Molecular Modeling and In Vitro Activity Study. [PDF]

Biomedicines
Drozdowska D, Wróbel-Tałałaj A, Parzych C, Ratkiewicz A.   +3 more
europepmc   +1 more source

Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus. [PDF]

Antimicrob Agents Chemother
Aragaw WW, Negatu DA, Bungard CJ, Dartois VA, Marrouni AE, Nickbarg EB, Olsen DB, Warrass R, Dick T.   +8 more
europepmc   +1 more source

Molecular modeling of the interactions of compounds of <i>Irvinga wombulu</i> against dihydrofolate reductase-thymidylate synthase in <i>Plasmodium falciparum</i> towards development of anti-malarial drug. [PDF]

In Silico Pharmacol
Chike-Ekwughe A, Abdulameed HT, Adebayo-Gege GI, Usman A, Omoyungbo EJ, Ala AA, Adegboyega AE, Johnson TO.   +7 more
europepmc   +1 more source

Solution Ionic Strength Can Modulate Functional Loop Conformations in E. coli Dihydrofolate Reductase. [PDF]

J Phys Chem B
Babu CS, Chen JY, Lim C.
europepmc   +1 more source

Synthesis, in vitro biological evaluation and in silico studies of novel pyrrolidine derived thiosemicarbazones as dihydrofolate reductase inhibitors. [PDF]

RSC Adv
Aftab H, Ullah S, Khan A, Al-Rashida M, Islam T, Alshammari A, Albekairi NA, Taslimi P, Al-Harrasi A, Shafiq Z, Alghamdi S.   +10 more
europepmc   +1 more source

Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate. [PDF]

PLoS Genet
Rouleau FD, Dubé AK, Gagnon-Arsenault I, Dibyachintan S, Pageau A, Després PC, Lagüe P, Landry CR.   +7 more
europepmc   +1 more source