Results 141 to 150 of about 9,730 (212)

Dihydroorotate Dehydrogenase Inhibitor ASLAN003 [PDF]

, 2020
openaire   +1 more source

Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase. [PDF]

Nat Commun, 2023
Zhan M, Ding Y, Huang S, Liu Y, Xiao J, Yu H, Lu L, Wang X.   +7 more
europepmc   +1 more source

Dihydroorotate Dehydrogenase Inhibitor BAY2402234 [PDF]

, 2020
openaire   +1 more source

Indazole and Benzoisoxazole Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia. [PDF]

ACS Med Chem Lett, 2022
Sabnis RW.
europepmc   +1 more source

Dihydroorotate dehydrogenase inhibition activates STING pathway and pyroptosis to enhance NK cell-dependent tumor immunotherapy. [PDF]

Mol Biomed
Hai Y, Lin R, Liao W, Fu S, Fan R, Ding G, Zhuang J, Zhang B, Liu Y, Song J, Wei G.   +10 more
europepmc   +1 more source

Dihydroorotate Dehydrogenase (Quinone), Mitochondrial [PDF]

, 2020
openaire   +1 more source

Evaluating the safety, pharmacokinetics, and antiparasitic activity of DSM265, a novel antimalarial plasmodium dihydroorotate dehydrogenase inhibitor: a systematic review and meta-analysis of early clinical trials. [PDF]

Malar J
Sula I, Jihwaprani MC, Ahmad I, Khan TA, Al Abdin MG, Ali MM, Ming LC.   +6 more
europepmc   +1 more source

A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor. [PDF]

Eur J Clin Pharmacol, 2023
Morton TL, Laskin OL, Kaushik D, Lee L, Ma J, Bar CM, Kristensen A, O'Keefe K, Golden L, Klein M, Kong R.   +10 more
europepmc   +1 more source

Barbituric Acid Derivatives as Covalent Inhibitors of <i>Leishmania braziliensis</i> Dihydroorotate Dehydrogenase. [PDF]

J Med Chem
Froes TQ, Alegbejo Price TO, Fleck Godoi B, Vaidergorn MM, Dos Santos T, Leite PIP, Silva DG, Dias da Purificação A, Loch L, Schenkman S, Kratz JM, da Silva Emery F, Nonato MC.   +12 more
europepmc   +1 more source

A pharmacokinetic drug-drug interaction study between rosuvastatin and emvododstat, a potent anti-SARS-CoV-2 (COVID-19) DHODH (dihydroorotate dehydrogenase) inhibitor. [PDF]

Pharmacol Res Perspect, 2023
Morton TL, Laskin OL, Kaushik D, Lee L, Ma J, Kristensen A, O'Keefe K, Golden L, Klein M, Kong R.   +9 more
europepmc   +1 more source