Results 131 to 140 of about 9,730 (212)

Dihydroorotate dehydrogenase (DHODH) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia

JCI Insight
Acute myeloid leukemia (AML) is a fatal disease characterized by the accumulation of undifferentiated myeloblasts, and agents that promote differentiation have been effective in this disease but are not curative.
Ola A. Elgamal, Sydney Fobare, Sandip Vibhute, Abeera Mehmood, Dennis C. Vroom, Mariah L. Johnson, Blaise Stearns, James R. Lerma, Jean Truxall, Emily Stahl, Bridget Carmichael, Shelley J. Orwick, Alice S. Mims, Emily Curran, Ramasamy Santhanam, Susheela Tridandapani, Mitch A. Phelps, Zhiliang Xie, Christopher C. Coss, Sharyn D. Baker, Jeffrey Patrick, Janel K. Ezzell, Jayesh Rai, Jianmin Pan, Shesh N. Rai, Cody Stillwell, Mark Wunderlich, Mouad Abdulrahim, Thomas E. Goodwin, Gerard Hilinski, Chad E. Bennett, Erin Hertlein, John C. Byrd   +32 more
doaj   +1 more source

Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway. [PDF]

CNS Neurosci Ther, 2023
Li D, Lu X, Xu G, Liu S, Gong Z, Lu F, Xia X, Jiang J, Wang H, Zou F, Ma X.   +10 more
europepmc   +1 more source

New Immunosuppressive Drugs: Mechanistic Insights and Potential Therapeutic Advances [PDF]

, 1993
Akselband Y., Allison A. C., Allison A. C., Amemiya H., Amemiya H., Amemiya H., Angus W. Thomson, Bogaerde J., Cho E. A., Chong A. S.-F., Clipstone N. A., Dutz J. P., Figueroa J., Flanagan W. M., Flanagan W. M., Francavilla A., Fruman D. A., Fruman D. A., Fuchs E. J., Fung J. J., Gregory C. R., Gudas V. M., Hao L., Hasan R., Kahan B. D., Kahan B. D., Kimball P. M., Kupiec-Weglinski J. W., Li-Weber M., Luo H., Makowka L., Makowka L., McCaffrey P. G., Morris R. E., Morris R. E., Morris R. E., Morris R. E., Murase N., Murase N., Murase N., Nelson P. A., Padova F. E., Peters D. H., Platz K. P, Price D. J., Propper D. J., Schmidbauer G., Schreiber S. L., Sehgal S. N., Smith M. R., Sollinger H. W., Sollinger H. W., Starzl T. E., Starzl T. E., Suzuki S., Tamura K., Thomas E. Starzl, Thomson A. W., Thomson A. W., Thomson A. W., Todo S., Wang S. C., Woo J., Woo J., Xiao F., Xu Q.   +65 more
core   +1 more source

The target site of the novel fungicide quinofumelin, Pyricularia oryzae class II dihydroorotate dehydrogenase. [PDF]

J Pestic Sci, 2022
Higashimura N, Hamada A, Ohara T, Sakurai S, Ito H, Banba S.   +5 more
europepmc   +1 more source

Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii. [PDF]

Proc Natl Acad Sci U S A, 2022
Russo TA, Umland TC, Deng X, El Mazouni F, Kokkonda S, Olson R, Carlino-MacDonald U, Beanan J, Alvarado CL, Tomchick DR, Hutson A, Chen H, Posner B, Rathod PK, Charman SA, Phillips MA.   +15 more
europepmc   +1 more source

Novel fungicide quinofumelin shows selectivity for fungal dihydroorotate dehydrogenase over the corresponding human enzyme. [PDF]

J Pestic Sci, 2023
Higashimura N, Hamada A, Banba S.
europepmc   +1 more source

Dihydroorotate dehydrogenase as a herbicide target

Proceedings of the National Academy of Sciences, 2023
openaire   +2 more sources

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity. [PDF]

J Nat Prod
Alberti M, Tamburello M, Salamone S, Gallinella G, Sanna C, Appendino GB, Lolli ML, Massarotti A, Pollastro F, Miggiano R.   +9 more
europepmc   +1 more source

Development of a biomarker to monitor target engagement after treatment with dihydroorotate dehydrogenase inhibitors. [PDF]

Biochem Pharmacol, 2022
Pontikos MA, Leija C, Zhao Z, Wang X, Kilgore J, Tornesi B, Adenmatten N, Phillips MA, Williams NS.   +8 more
europepmc   +1 more source