Results 111 to 120 of about 9,730 (212)

Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca: De Novo Assembly and Analysis of Novel Toxic Proteins

Toxins
Previous proteomic studies of viperid venom revealed that it is mainly composed of metalloproteinases (SVMPs), serine proteinases (SVSPs), phospholipase A2 (PLA2), and C-type lectins (CTLs).
Joseph Espín-Angulo, Doris Vela
doaj   +1 more source

Action mechanism of a novel agrichemical quinofumelin against Fusarium graminearum

eLife
Modern fungicides have made significant contributions to crop disease management, but the development of resistant fungal strains has caused their failure in disease control.
Qian Xiu, Xiaoru Yin, Yuanyuan Chen, Ziyang Zhang, Yushuai Mao, Tianshi Wang, Jie Zhang, Mingguo Zhou, Yabing Duan   +8 more
doaj   +1 more source

Identification of a New Chemical Class of Antimalarials [PDF]

, 2017
The increasing spread of drug-resistant malaria strains underscores the need for new antimalarial agents with novel modes of action (MOAs). Here, we describe a compound representative of a new class of antimalarials.
Aissaoui, Hamed, Binkert, Christoph, Boss, Christoph, Bozdech, Zbynek, Brun, Reto, Brunner, Ralf, Corminboeuf, Olivier, Delahaye, Stephane, Fischli, Christoph, Heidmann, Bibia, Kaiser, Marcel, Kamber, Jolanda, Meyer, Solange, Papastogiannidis, Petros, Siegrist, Romain, Voss, Till, Welford, Richard, Wittlin, Sergio   +17 more
core  

Dihydroorotate dehydrogenase (DHODH) [PDF]

Science-Business eXchange, 2011
openaire   +3 more sources

Mysteries of partial dihydroorotate dehydrogenase inhibition and leukemia terminal differentiation

Haematologica, 2020
Yogen Saunthararajah
doaj   +1 more source

Exploring the antifungal potential of Cannabis sativa-derived stilbenoids and cannabinoids against novel targets through in silico protein interaction profiling

Frontiers in Chemistry
Cannabinoid and stilbenoid compounds derived from Cannabis sativa were screened against eight specific fungal protein targets to identify potential antifungal agents.
Kevser Kübra Kırboğa, Aman Karim, Ecir Uğur Küçüksille, Mithun Rudrapal, Johra Khan, Raghu Ram Achar, Ekaterina Silina, Natalia Manturova, Victor Stupin   +8 more
doaj   +1 more source

Crystalline Dihydroorotic Dehydrogenase

Journal of Biological Chemistry, 1960
H C, FRIEDMANN, B, VENNESLAND
openaire   +2 more sources

Dihydroorotate Dehydrogenase

Journal of Biological Chemistry, 1967
Victor Aleman, Philip Handler
openaire   +1 more source

Discovery of Novel Inhibitors of Aspergillus fumigatus DHODH via Virtual Screening, MD Simulation, and In Vitro Activity Assay

Molecules
To address the surge in Aspergillus fumigatus infections among immunosuppressed patients and azole resistance, this study focused on developing novel inhibitors targeting dihydroorotate dehydrogenase (AfDHODH), a key enzyme in fungal pyrimidine synthesis.
Kaige Li, Wei Xia, John Z. H. Zhang
doaj   +1 more source

Dihydroorotate Dehydrogenase

Journal of Biological Chemistry, 1966
Richard W. Miller, Carolyn T. Kerr
openaire   +1 more source