Results 151 to 160 of about 9,730 (212)

Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol. [PDF]

ACS Omega
Purificação AD, Benz LS, Lima Silva WJ, Emery FS, Andrade CH, Weiss MS, Nonato MC.   +6 more
europepmc   +1 more source

Biaryl Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML). [PDF]

ACS Med Chem Lett, 2022
Sabnis RW.
europepmc   +1 more source

Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide. [PDF]

Acta Crystallogr F Struct Biol Commun
Agarwal AA, Georgiades JD, Dranow DM, Lorimer DD, Edwards T, Barrett KF, Craig JK, Van Voorhis WC, Myler PJ, Smith CL.   +9 more
europepmc   +1 more source

Molecular Dynamics Studies on <i>Trypanosoma cruzi</i> Dihydroorotate Dehydrogenase Complexes: An Analysis of the Inhibitor Influence. [PDF]

ACS Omega
Santos EG, Flores-Junior LAP, Lima CHS, Dias LRS.   +3 more
europepmc   +1 more source

Heterocyclic Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML). [PDF]

ACS Med Chem Lett, 2021
Sabnis RW.
europepmc   +1 more source

A phase 1, first-in-human, dose-escalation study of JNJ-74856665 (dihydroorotate dehydrogenase inhibitor) alone or in combination in patients with AML or MDS. [PDF]

Br J Haematol
Searle E, Cluzeau T, O'Nions J, Recher C, Gyan E, Morillo D, Esteve J, Kulasekararaj A, Raffoux E, Walter HS, Pigneux A, Valcárcel D, Daskalakis N, Bussolari J, Pietsch EC, Kuduk S, Bush T, Zhang X, Philippar U, Oluwasanjo A, Bradford K, Miller J, Van Bogaert C, Curtis M, Chang SY, Guttke C, Gaj S, Pearson R, Murphy J, van Dijck W, Alfonso Piérola A.   +30 more
europepmc   +1 more source

Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification. [PDF]

Front Cell Dev Biol, 2023
Al-Akashi Z, Zujur D, Kamiya D, Kato T, Kondo T, Ikeya M.   +5 more
europepmc   +1 more source

On the interactions of leflunomide and teriflunomide within receptor cavity — NMR studies and energy calculations [PDF]

, 2015

core   +1 more source

Correction: Zhao et al. <i>Bombyx mori</i> Dihydroorotate Dehydrogenase: Knockdown Inhibits Cell Growth and Proliferation via Inducing Cell Cycle Arrest. <i>Int. J. Mol. Sci.</i> 2018, <i>19</i>, 2581. [PDF]

Int J Mol Sci
Zhao E, Jiang X, Cui H.
europepmc   +1 more source

Discovery of potential natural dihydroorotate dehydrogenase inhibitors and their synergism with brequinar via integrated molecular docking, dynamic simulations and in vitro approach. [PDF]

Sci Rep, 2022
Khairy A, Hammoda HM, Celik I, Zaatout HH, Ibrahim RS.   +4 more
europepmc   +1 more source