Results 11 to 20 of about 4,532 (195)

Oxidative Aromatization of Some 1,4-Dihydropyridine Derivatives Using Pyritic Ash in Eco-Sustainable Conditions

Chemistry Proceedings, 2023
Hantzsch 1,4-dihydropyridines (Hantzsch 1,4-DHP), have been utilized as starting material in organic synthesis. In addition, several 1,4-DHP based drugs (Nifedipine, Niguldipine, Amlodepine besylate) have been recognized for the treatment of ...
Juan Enrique Tacoronte Morales, Carla Bernal Villavicencio, Xavier Leopoldo Gracia Cervantes, Maria Elizabeth Canchingre, Maria Teresa Cabrera Pedroso   +4 more
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Design, Synthesis, and Biological Evaluation of Novel Dihydropyridine and Pyridine Analogs as Potent Human Tissue Nonspecific Alkaline Phosphatase Inhibitors with Anticancer Activity: ROS and DNA Damage-Induced Apoptosis

Molecules, 2022
Small molecules with nitrogen-containing scaffolds have gained much attention due to their biological importance in the development of new anticancer agents. The present paper reports the synthesis of a library of new dihydropyridine and pyridine analogs
Nazeer Ahmad Khan, Faisal Rashid, Muhammad Siraj Khan Jadoon, Saquib Jalil, Zulfiqar Ali Khan, Raha Orfali, Shagufta Perveen, Areej Al-Taweel, Jamshed Iqbal, Sohail Anjum Shahzad   +9 more
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Zinc (II)-Mediated Selective O-Benzylation of 2-Oxo-1,2-Dihydropyridines Systems

Molecules, 2018
The selective O-benzylation of 2-oxo-1,2-dihydropyridines plays a critical role in organic synthesis of natural products and biological active molecules.
Qifan Zhou, Fangyu Du, Xinjie Liang, Wenqiang Liu, Ting Fang, Guoliang Chen   +5 more
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Benign synthesis of therapeutic agents: domino synthesis of unsymmetrical 1,4-diaryl-1,4-dihydropyridines in the ball-mill

Green Chemistry Letters and Reviews, 2022
The solvent-free preparation of unsymmetrical N-aryl-5,6-unsubstituted-1,4-dihydropyridines (DHPs) by ball-milling was investigated. Three different mechanochemical domino reactions (one-pot/one step or stepwise) were studied, the process parameters ...
Cristina Blazquez-Barbadillo, Juan Francisco González, Andrea Porcheddu, David Virieux, José Carlos Menéndez, Evelina Colacino   +5 more
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Synthesis and anticholinesterase activity of a novel series of acetazolamide condensed 1,4-dihydropyridines

Carbon Resources Conversion, 2019
A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation of the
Mudduluru Niranjan Babu, Karthikeyan Elumalai, Sivaneswari Srinivasan, Kalpana Eluri, Manogaran Elumalai, Srinivasan Sivannan   +5 more
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Antimicrobial Activity of Some Derivatives of 1,4-Dihydropyridines

Journal of Chemistry, 2013
Hantzsch reported the synthesis of functionalized 1,4-dihydropyridines via three-component condensation of an aromatic aldehyde, ketoester, and ammonium hydroxide.
Prabha Mehta, Prabha Verma
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In vitro bactericidal activities of two novel dihydropyridine derivatives against Mycobacterium tuberculosis

Journal of Infection in Developing Countries, 2017
Introduction: Introducing new and effective antitubercular agents is important in tuberculosis control programs. In this study, the in vitro antitubercular activity of two novel 1,4-dihydropyridine derivatives (F-27, Cl-33) were screened against a total
Mehdi Zandhaghighi, Farzin Hadizadeh, Saman Soleimanpour, Zahra Meshkat, Seyed Abdolrahim Rezaee, Mohammad Derakhshan, Kiarash Ghazvini   +6 more
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An Efficient Method for The Synthesis of Dihydropyridine by Hantzsch Reaction with Fe/SiO2 Nano Heterogeneous Catalysts

Bulletin of Chemical Reaction Engineering & Catalysis, 2020
An efficient method for the synthesis of dihydropyridines (DHPs) by Hantzsch reaction with Fe/SiO2 heterogeneous catalysts was developed. The Fe/SiO2 catalysts was prepared by impregnation method.
Ateeq Rahman, P. N. Nehemia, Moola M. Nyambe   +2 more
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The unique reactivity of 5,6-unsubstituted 1,4-dihydropyridine in the Huisgen 1,4-diploar cycloaddition and formal [2 + 2] cycloaddition

Beilstein Journal of Organic Chemistry, 2023
The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen, Hui Zheng, Ying Han, Jing Sun, Chao-Guo Yan   +4 more
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STROKE PREVENTION OPPORTUNITIES FOR CARDIOLOGISTS: COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION (ROLE OF CALCIUM ANTAGONISTS)

Кардиоваскулярная терапия и профилактика, 2013
The paper focuses on the important issue of cardio-cerebral interactions, cardiac comorbidities, and the need for complex therapeutic approaches. While stroke is traditionally regarded as a neurologic problem, cardiologists play an important role in its ...
E. O. Taratukhin
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