Results 21 to 30 of about 4,506 (161)

Design, Synthesis, and Biological Evaluation of Novel Dihydropyridine and Pyridine Analogs as Potent Human Tissue Nonspecific Alkaline Phosphatase Inhibitors with Anticancer Activity: ROS and DNA Damage-Induced Apoptosis

Molecules, 2022
Small molecules with nitrogen-containing scaffolds have gained much attention due to their biological importance in the development of new anticancer agents. The present paper reports the synthesis of a library of new dihydropyridine and pyridine analogs
Nazeer Ahmad Khan, Faisal Rashid, Muhammad Siraj Khan Jadoon, Saquib Jalil, Zulfiqar Ali Khan, Raha Orfali, Shagufta Perveen, Areej Al-Taweel, Jamshed Iqbal, Sohail Anjum Shahzad   +9 more
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Zinc (II)-Mediated Selective O-Benzylation of 2-Oxo-1,2-Dihydropyridines Systems

Molecules, 2018
The selective O-benzylation of 2-oxo-1,2-dihydropyridines plays a critical role in organic synthesis of natural products and biological active molecules.
Qifan Zhou, Fangyu Du, Xinjie Liang, Wenqiang Liu, Ting Fang, Guoliang Chen   +5 more
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Benign synthesis of therapeutic agents: domino synthesis of unsymmetrical 1,4-diaryl-1,4-dihydropyridines in the ball-mill

Green Chemistry Letters and Reviews, 2022
The solvent-free preparation of unsymmetrical N-aryl-5,6-unsubstituted-1,4-dihydropyridines (DHPs) by ball-milling was investigated. Three different mechanochemical domino reactions (one-pot/one step or stepwise) were studied, the process parameters ...
Cristina Blazquez-Barbadillo, Juan Francisco González, Andrea Porcheddu, David Virieux, José Carlos Menéndez, Evelina Colacino   +5 more
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Synthesis and anticholinesterase activity of a novel series of acetazolamide condensed 1,4-dihydropyridines

Carbon Resources Conversion, 2019
A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation of the
Mudduluru Niranjan Babu, Karthikeyan Elumalai, Sivaneswari Srinivasan, Kalpana Eluri, Manogaran Elumalai, Srinivasan Sivannan   +5 more
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Antimicrobial Activity of Some Derivatives of 1,4-Dihydropyridines

Journal of Chemistry, 2013
Hantzsch reported the synthesis of functionalized 1,4-dihydropyridines via three-component condensation of an aromatic aldehyde, ketoester, and ammonium hydroxide.
Prabha Mehta, Prabha Verma
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In vitro bactericidal activities of two novel dihydropyridine derivatives against Mycobacterium tuberculosis

Journal of Infection in Developing Countries, 2017
Introduction: Introducing new and effective antitubercular agents is important in tuberculosis control programs. In this study, the in vitro antitubercular activity of two novel 1,4-dihydropyridine derivatives (F-27, Cl-33) were screened against a total
Mehdi Zandhaghighi, Farzin Hadizadeh, Saman Soleimanpour, Zahra Meshkat, Seyed Abdolrahim Rezaee, Mohammad Derakhshan, Kiarash Ghazvini   +6 more
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An Efficient Method for The Synthesis of Dihydropyridine by Hantzsch Reaction with Fe/SiO2 Nano Heterogeneous Catalysts

Bulletin of Chemical Reaction Engineering & Catalysis, 2020
An efficient method for the synthesis of dihydropyridines (DHPs) by Hantzsch reaction with Fe/SiO2 heterogeneous catalysts was developed. The Fe/SiO2 catalysts was prepared by impregnation method.
Ateeq Rahman, P. N. Nehemia, Moola M. Nyambe   +2 more
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STROKE PREVENTION OPPORTUNITIES FOR CARDIOLOGISTS: COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION (ROLE OF CALCIUM ANTAGONISTS)

Кардиоваскулярная терапия и профилактика, 2013
The paper focuses on the important issue of cardio-cerebral interactions, cardiac comorbidities, and the need for complex therapeutic approaches. While stroke is traditionally regarded as a neurologic problem, cardiologists play an important role in its ...
E. O. Taratukhin
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Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles

Acta Chimica Slovenica, 2022
The efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C.
Somayeh Moradi, Mohsen Moradian, Hossein Naeimi   +2 more
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Selective Mono Bromination of 1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei, Adeleh Moshtaghi Zenouz   +1 more
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