Results 51 to 60 of about 332 (138)

Tolerability of high doses of lercanidipine versus high doses of other dihydropyridines in daily clinical practice: the TOLERANCE Study

Кардиоваскулярная терапия и профилактика, 1970
Aim. The TOLERANCE study was aimed to compare the tolerability of high doses of lercanidipine (20 mg) with that of other frequently used dihydropyridines (amlodipine 10 mg/nifedipine GITS 60 mg) in the treatment of essential hypertension (EAH) in daily ...
V. Barrios, C. Escobar, M. de la Figuera, J. L. Llisterri, J. Honorato, J. Segura, A. Calderón   +6 more
doaj  

N,N'-Ethylene-bis(benzoylacetoniminato) Copper (II), Cu(C22H22N2O2), a New Reagent for Aromatization of Hantzsch 1,4-Dihydropyridines

Molecules, 2007
A variety of Hantzsch 1,4-dihydropyridines were oxidized to their corresponding pyridines in high yields in the presence of Cu(C22H22N2O2) in refluxing acetic acid.
Majid M Heravi, Saeed Dehghanpour, Fatemeh Derikvand   +2 more
doaj   +1 more source

Genetic and Pharmacologic Inhibition of Myostatin Restores Muscle Mass in a Dynamin 2‐Related Centronuclear Myopathy Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Autosomal dominant centronuclear myopathy (ADCNM), most commonly caused by mutations in the dynamin 2 (DNM2) gene, is a rare congenital myopathy characterized by progressive muscle weakness and atrophy. Myostatin, a key negative regulator of skeletal muscle mass, has shown therapeutic potential in several models of neuromuscular ...
Durieux Anne‐Cécile, Arnould David, Velarde Mathias, Allibert Valentine, Paret Chloé, Debelley Quentin, Kizilkilic Esra, Chambon Sidney, Girard Emmanuelle, Collin Louise, Gensel Alexandre, Castells Josiane, Pasternack Aja, Bowen Maximilien, Morel Baptiste, Hourdé Christophe, Laurent Schaeffer, Ritvos Olli, Bitoun Marc, Mounier Rémi, Freyssenet Damien   +20 more
wiley   +1 more source

Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems

Beilstein Journal of Organic Chemistry, 2012
An efficient three component reaction with enaminones, primary amines and aldehydes resulted in easy access to 1,4-dihydropyridines with different substituents at the 1-, 3-, 4- and 5-positions.
Nouria A. Al-Awadi, Maher R. Ibrahim, Mohamed H. Elnagdi, Elizabeth John, Yehia A. Ibrahim   +4 more
doaj   +1 more source

A Microwave-Assisted Bismuth Nitrate-Catalyzed Unique Route Toward 1,4-Dihydropyridines

Molecules, 2012
The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives.
Bimal K. Banik, Stephanie Maldonado, Debasish Bandyopadhyay   +2 more
doaj   +1 more source

One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity

Beilstein Journal of Organic Chemistry, 2020
A rapid route for obtaining unsymmetrical 1,2-dihydropyridines (1,2-DHPs) as opposed to 1,4-dihydropyridines (1,4-DHPs) has been achieved via a one-pot multicomponent Hantzsch reaction.
Giovanna Bosica, Kaylie Demanuele, José M. Padrón, Adrián Puerta   +3 more
doaj   +1 more source

Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9336-9345, October 2026.
ABSTRACT Aims To evaluate whether initiation of amiodarone while receiving sulfonylurea is associated with an increased risk of severe hypoglycemia compared with the initiation of other antiarrhythmic agents (flecainide, sotalol, or propafenone) while receiving sulfonylurea. Materials and Methods We conducted a population‐based cohort study using South
Sungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov   +5 more
wiley   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, Volume 11, Issue 17, 3 September 2026.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Amiodarone‐ and Lithium‐Induced Thyroid Dysfunction—Prescriber Specialties Involved in Potential Prescribing Cascades: A Retrospective Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Prescribing cascades occur when an adverse drug reaction (ADR) leads to the prescription of additional medications. It remains unclear whether different prescribers are involved in potential prescribing cascades that develop over time and whether ADRs are communicated across the care continuum.
J. de Ruijter – van Dalem, M. de Weerd – Slot, M. H. Schipper, C. E. H. Siegert, A. Marmorale, M. L. Becker, F. Karapinar‐Çarkit   +6 more
wiley   +1 more source

Hantzsch Reaction Starting Directly from Alcohols through a Tandem Oxidation Process

Journal of Chemistry, 2017
A Brønsted acidic ionic liquid, 3-(N,N-dimethyldodecylammonium) propanesulfonic acid hydrogen sulphate ([DDPA][HSO4]), has been successfully applied to catalyze sequential oxidation of aromatic alcohols with NaNO3 followed by their condensation with ...
Xiaobing Liu, Bin Liu
doaj   +1 more source