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Oxidation of Hantzsch 1,4- Dihydropyridines to Pyridines with Thallium Triacetate [PDF]
Hantzsch 1, 4-dihydropyridines (1,4-DHPs) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.
Mohammad Mahmoodi Hashemi +2 more
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Small-molecule screens can advance therapeutic discovery and uncover new features of pathogen biology. Through a luminescence-based screen, we identified clinically approved dihydropyridines that impaired fitness of the intracellular pathogen Brucella ...
Thomas Kim +7 more
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Sodium Hypochlorite-Dowex 1X8-200: A Convenient Oxidizing Reagant [PDF]
The polymer supported hypochlorite ion is a facile selective oxidizing agent for the oxidation of various alcohols to aldehydes and ketones. Similarly is successfully oxidizes various Hantzsch type 1,4- dihydropyridines to corresponding pyridines.
Mahammad Mahmoodi Hashemi +1 more
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Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei +1 more
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AROMATIZATION OF 1,4-DIHYDROPYRIDINES WITH FREE RADICAL REAGENTS [PDF]
Oxidation of different types of 1,4-dihydropyridines with diphenylpicrylhydrazyl (DPP) and benzoyl peroxide (Bz2O2) as free radical oxidizing agents to pyridine derivatives is reported and a mechanism for this oxidation is also proposed.
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AROMATIZATION OF 1 , CDIHYDROPYRIDINES WITH OXYGEN OR AIR USING MANGANESE AND COBALT SALTS OF p-AMINOBENZOIC ACID SUPPORTED ON SILICA GEL AS OXIDIZING CATALYSTS [PDF]
Hantzsch 1,4-dihydropyridines are oxidized to the corresponding pyridine derivatives using oxygen or air and a mixture of the manganese and cobalt salts of parninobenzoic acid supported on silica gel as the catalysts.
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ChemInform Abstract: 1,2‐Dihydropyridines, 1,4‐Dihydropyridines, and Derivatives
ChemInform, 2009AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
J.‐C. Quirion, E. Leclerc, P. Jubault
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(Trihalogenmethyl)dihydropyridine
Chemische Berichte, 1977Abstract1‐(2,6‐Dichlorbenzyl)‐ und 1‐Ethylpyridinium‐Salze ergeben mit Haloformat‐Anionen (Trihalogenmethyl)dihydropyridine. Je nach dem verwendeten Haloform werden primär nur die 1,2‐ oder die 1,4‐Dihydropyridine gebildet. Die 2‐(Trichlormethyl)‐1,2‐dihydropyridine 1 lagern sich in polaren, aprotischen Lösungsmitteln in die 4‐(Trichlormethyl)‐1,4 ...
Karl Heinz Duchardt, Fritz Kröhnke
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1,4-Dihydropyridines and the 1,4-Dihydropyridine Receptor
1993The 1,4-dihydropyridine nifedipine is a first-generation drug of major significance in the treatment of cardiovascular disorders including hypertension, peripheral vascular disorders and angina in its several forms. Nifedipine is one of a chemically and pharmacologically heterogeneous group of drugs that includes also verapamil and diltiazem and which ...
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