Results 71 to 80 of about 4,532 (195)

A Case Report of PR Interval Prolongation Caused by Amlodipine

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Amlodipine is a widely used dihydropyridine calcium channel blocker. Its effects on the cardiac conduction system, especially PR interval prolongation, are rare but clinically important. We report a 25‐year‐old healthy male subject in a clinical trial with baseline first‐degree atrioventricular block (PR interval 230 ms).
Zhiying Fu, Suping Ling, Xiaoli Ji, He Zhu   +3 more
wiley   +1 more source

Persistent Arrhythmogenic Effects of COVID‐19: A Comprehensive Analysis of Device Implantation and Antiarrhythmic Interventions in Japan

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
COVID‐19 was associated with a sustained increase in device implantation and arrhythmia‐related interventions over 2 years. In a nationwide propensity score‐matched cohort, risks of pacemaker, ICD, CRT implantation, ablation procedures, and antiarrhythmic medication initiation remained higher after COVID‐19, supporting long‐term cardiovascular ...
Daisuke Miyamori, Shuhei Yoshida, Masanori Ito   +2 more
wiley   +1 more source

Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers

Кардиоваскулярная терапия и профилактика, 2010
Background. Results from clinical studies suggest that the dihydropyridine calcium channel blocker (d-CCB) lercanidipine may be associated with a lower incidence of peripheral edema than are older d-CCBs. Aim. To conduct a meta-analysis of published data
K. Makarounas-Kirchmann, S. Glover-Koudounas, P. Ferrari   +2 more
doaj  

A multifaceted approach for the development of novel Hantzsch 1,4-dihydropyridines as anticancer agents: Rational design, parallel synthesis, analysis, cytotoxicity and EGFR/HER2 inhibition studies

Results in Chemistry
Dihydropyridines (DHPs) exhibit a wide range of pharmacological properties especially against cancer. In this context, a new series of 1,4-dihydropyridines were meticulously designed employing scaffold hybridization technique targeting the EGFR/HER2 ...
A.S.V.L. Sruthi, Syed Faizan, Hemant Vikram, N.G. Veena, Aishwarya Susil, Haritha Harindranath, S. Vasanth Kumar, Vasanth Kumar Shivaraju, B.R. Prashantha Kumar   +8 more
doaj   +1 more source

Identification and characterization of the dihydropyridine-binding subunit of the skeletal muscle dihydropyridine receptor.

Journal of Biological Chemistry, 1987
Photoaffinity labeling of isolated triads and purified dihydropyridine receptor with [3H]azidopine and (+)-[3H]PN200-110 has been used to identify and characterize the dihydropyridine-binding subunit of the 1,4-dihydropyridine receptor of rabbit skeletal muscle.
A H, Sharp, T, Imagawa, A T, Leung, K P, Campbell   +3 more
openaire   +2 more sources

Comparative Effectiveness and Safety of Three Oral Antihypertensive Therapies on Maternal and Infant Outcomes in a California Medicaid Population, 2016–2020

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Purpose To extend the Chronic Hypertension and Pregnancy (CHAP) trial findings, this study compared labetalol, nifedipine, and methyldopa initiation at or before 23 weeks' gestation in pregnant patients with chronic hypertension, examining effects on a composite effectiveness outcome and on small for gestational age birth (SGA).
Catherine Psaras, Erin Delker, Rebecca J. Baer, Clare M. Cutri‐French, Gretchen Bandoli   +4 more
wiley   +1 more source

The role of amlodipine (norvasc) in Cardiology

КардиоСоматика, 2014
The review concerns amlodipine - the representative of the third generation of dihydropyridines. Amlodipine, being considered a hypotensive drug, has a broad spectrum of clinical effects beyond the hypotensive effects.
D. M Aronov
doaj  

Role of novel automated methods in pulse signal analysis to screen for sleep‐disordered breathing among patients on chronotropic medications

Sleep Research, Volume 3, Issue 2, Page 98-107, June 2026.
Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed, Moustafa Habra, Raya Nashef, Scott Maresh, Abed Najjar, Shivapriya Chandu, Adhithi Athikumar, Omar Ismail, Laurel A. Ravelo, Paul E. Peppard, M. Safwan Badr, Abdulghani Sankari   +11 more
wiley   +1 more source

Oxidation of Hantzsch 1,4- Dihydropyridines to Pyridines with Thallium Triacetate [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2003
Hantzsch 1, 4-dihydropyridines (1,4-DHPs) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.
Mohammad Mahmoodi Hashemi, Mohammad Sadegh Zakeri, Saeed Arianfar   +2 more
doaj  

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

Internal Medicine Journal, Volume 56, Issue 6, Page 966-975, June 2026.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich, W. P. Abhayaratna, R. Audehm, E. I. Ekinci, R. J. MacIsaac, A. J. Nelson, A. Sharma, C. Pollock   +7 more
wiley   +1 more source