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Asymmetric Synthesis of Medicinally Important Dihydropyrimidinones
The Biginelli reaction is considered one of the well-known examples of a multicomponent reaction that is useful in the synthesis of dihydropyrimidinones (DHPMs) using aryl aldehydes, urea, and esters and these are significant compounds in medicinal chemistry and chemical synthesis.Rajni Sharma +2 more
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Tetrahydroindolone‐Dihydropyrimidinone Hybrids as Promising Antibiofilm and Antibacterial Agents
ChemMedChemIn the pursuit of novel therapeutic agents with enhanced antimicrobial properties, a new series of hybrid compounds combining the tetrahydroindolones and dihydropyrimidinones scaffolds is designed and synthesized in good yields. The hybridization strategy aims to merge the distinct biological functionalities of each pharmacophore ...
Vinicius Vendrusculo +6 more
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Synthesis and ct-DNA binding study of a donor-π-acceptor dihydropyrimidinone fluorophore
Journal of Molecular Structure, 2023Mohabul Alam Mondal
exaly