Results 151 to 160 of about 611 (196)

Dihydropyrimidinones containing boronic acids

Canadian Journal of Chemistry, 2005
The addition of formylphenylboronic acid derivatives to urea and ethyl acetoacetate proceeds in the absence of an additional Lewis acid catalyst to give the corresponding dihydropyrimidinones (Biginelli products) in good yields. Novel boron-containing dihydropyrimidinones have been investigated for their ability to act as anticancer agents against the
Johanna M Blacquiere, Oana Sicora, Christopher M Vogels, Miroslava Čuperlović-Culf, Andreas Decken, Rodney J Ouellette, Stephen A Westcott   +6 more
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Dihydropyrimidinones—a new class of anti-Staphylococcal antibiotics

Bioorganic & Medicinal Chemistry Letters, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Michael, Brands, Rainer, Endermann, Reinhold, Gahlmann, Jochen, Krüger, Siegfried, Raddatz   +4 more
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A recent update on the synthesis of dihydropyrimidinones/thiones

AIP Conference Proceedings, 2021
Since its development in 1891 Biginelli’s three component synthesis of dihydropyrimidinones/ thiones, it is always on highlight of synthetic organic chemist. A variety of catalysts such as Lewis acid, organocatalyst, Bronsted acid catalyst, ionic liquid catalyst, microwave irradiation methods, ultrasound irradiation methods, grinding and solvent-free ...
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Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones

Bioorganic & Medicinal Chemistry Letters, 2008
Copper (II) chloride in the absence of any solvent, efficiently catalyses the synthesis of dihydropyrimidinones (80-96% yields) by the Biginelli reaction. Six compounds were selected and examined their antifungal activities against the radial growth of three fungal species viz., Trichoderma hammatum, Trichoderma koningii and Aspergillus niger.
Okram Mukherjee, Singh, Sarangthem Joychandra, Singh, Mutum Babita, Devi, Laitonjam Nalini, Devi, Nameirakpam Irabanta, Singh, Sang-Gyeong, Lee   +5 more
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Evaluation of Electrochemical Behavior and Antioxidant Activity of Seleno‐Dihydropyrimidinones and Chloro‐Dihydropyrimidinones

ChemistrySelect
Abstract Organic compounds with potential antioxidant activity have attracted special attention of researchers and they have been widely studied in several areas, including pharmacology and medicinal chemistry. In this context, electrochemistry through cyclic voltammetry becomes a fast and efficient tool for the ...
Luiz Fernando Eltz da Rosa, Matheus Henrique Oliveira de Sousa, Mário Alf da Rosa, Neusa Fernandes de Moura, Carlos R. M. Peixoto, Rômulo Faria Santos Canto, Marcelo Godoi   +6 more
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Dihydropyrimidinone NPY Y1 Receptor Antagonists [PDF]

, 2003
Graham S. Poindexter, Marc A. Bruce, Graham Johnson, Lawrence G. Iben, Rachel T. McGovern, Gail K. Mattson, Ildiko Antal-Zimanyi   +6 more
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Substitutional effects on the reactivity and thermal stability of dihydropyrimidinones

Journal of Molecular Structure, 2021
Abstract One of the advantages of dihydropyrimidinones (DHPMs) is the molecular diversity that could be achieved through their synthesis from a three-component reaction by varying the starting reaction materials. Differences in substituted functional groups could lead to varying reactivities and thermal stability amongst the analogues. In this study,
Rasheed A. Adigun, Frederick P. Malan, Mohammed O. Balogun, Natasha October   +3 more
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Asymmetric alkylations of n-acyl dihydropyrimidinones

Tetrahedron: Asymmetry, 1991
Abstract Enantiomerically pure dihydropyrimidin-4-one 1 has been employed as a chiral auxiliary for enantioselective alkylation reactions. Acylation of 1 , followed by enolate formation, alkylation and acyl cleavage, affords α-alkylated carboxylic acids in high chemical yield and enatiomeric purity.
George R. Negrete, Joseph P. Konopelski
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One‐Pot Construction of Dihydropyrimidinones in Ionic Liquids.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sushilkumar S. Bahekar, Sandip A. Kotharkar, Devanand B. Shinde   +2 more
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A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Chemical Communications, 2007
A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.
Chris D, Bailey, Chris E, Houlden, Grégory L J, Bar, Guy C, Lloyd-Jones, Kevin I, Booker-Milburn   +4 more
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