Results 161 to 170 of about 1,311 (206)
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The Biginelli Dihydropyrimidinone Synthesis
ChemInform, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
C. Oliver Kappe, Alexander Stadler
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A Versatile Synthesis of DihydropyrimidinoneC‐Nucleosides
Nucleosides, Nucleotides and Nucleic Acids, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Ram Chandra, Mishra +3 more
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Stereoselective synthesis of new dihydropyrimidinone glycoconjugates #
Journal of Heterocyclic Chemistry, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
G. V. M. Sharma +3 more
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Dihydropyrimidinones containing boronic acids
Canadian Journal of Chemistry, 2005The addition of formylphenylboronic acid derivatives to urea and ethyl acetoacetate proceeds in the absence of an additional Lewis acid catalyst to give the corresponding dihydropyrimidinones (Biginelli products) in good yields. Novel boron-containing dihydropyrimidinones have been investigated for their ability to act as anticancer agents against the
Johanna M Blacquiere +6 more
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Dihydropyrimidinones—a new class of anti-Staphylococcal antibiotics
Bioorganic & Medicinal Chemistry Letters, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Michael, Brands +4 more
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A recent update on the synthesis of dihydropyrimidinones/thiones
AIP Conference Proceedings, 2021Since its development in 1891 Biginelli’s three component synthesis of dihydropyrimidinones/ thiones, it is always on highlight of synthetic organic chemist. A variety of catalysts such as Lewis acid, organocatalyst, Bronsted acid catalyst, ionic liquid catalyst, microwave irradiation methods, ultrasound irradiation methods, grinding and solvent-free ...
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Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones
Bioorganic & Medicinal Chemistry Letters, 2008Copper (II) chloride in the absence of any solvent, efficiently catalyses the synthesis of dihydropyrimidinones (80-96% yields) by the Biginelli reaction. Six compounds were selected and examined their antifungal activities against the radial growth of three fungal species viz., Trichoderma hammatum, Trichoderma koningii and Aspergillus niger.
Okram Mukherjee, Singh +5 more
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Synthesis and anticancer activity of new dihydropyrimidinone derivatives
European Journal of Medicinal Chemistry, 2018A series of dihydropyrimidinone derivatives bearing various N-heterocyclic moieties was designed and synthesized. Twelve new compounds were screened for their cytotoxic activity using 60 cancer cell lines according to NCI (USA) protocol. Compound 19 showed a significant activity against NCI-H460, SK-MEL-5, and HL-60 (TB) cell lines with growth ...
Amany S. Mostafa, Khalid B. Selim
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Asymmetric alkylations of n-acyl dihydropyrimidinones
Tetrahedron: Asymmetry, 1991Abstract Enantiomerically pure dihydropyrimidin-4-one 1 has been employed as a chiral auxiliary for enantioselective alkylation reactions. Acylation of 1 , followed by enolate formation, alkylation and acyl cleavage, affords α-alkylated carboxylic acids in high chemical yield and enatiomeric purity.
George R. Negrete, Joseph P. Konopelski
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A chemo- and regio-selective three-component dihydropyrimidinone synthesis
Chemical Communications, 2007A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.
Chris D, Bailey +4 more
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