Results 11 to 20 of about 20,405 (323)

Multi-molecular imaging showing tumour heterogeneity and differing diagnostic performance in a case with metastatic pheochromocytoma [PDF]

EJNMMI Reports
A patient with multiple endocrine neoplasia 2A (MEN2A) and a suspicion of metastasized pheochromocytoma, underwent multi-molecular positron emission tomography (PET) imaging with the recently presented radiopharmaceutical [18F]-metafluorobenzylguanidine (
Fredrik Hedeer, Jenny Oddstig, Páll Hallgrimson, Katarina Fagher   +3 more
doaj   +2 more sources

Dihydroxyphenylalanine-conjugated high molecular weight polyethylenimine for targeted delivery of Plasmid [PDF]

Scientific Reports
High molecular weight polyethylenimine (HMW PEI; branched 25 kDa PEI) has been widely investigated for gene delivery due to its high transfection efficiency.
Zahra Taheri, Maryam Kazemi, Bahman Khalvati, Farshad Safari, Samira Hossaini Alhashemi, Fatemeh Ahmadi, Ali Dehshahri   +6 more
doaj   +2 more sources

Disruption of the l-DOPA Receptor Gpr143/OA1-Gene in Mice Creates a Unique Mixed Psychosis-Like Phenotype. [PDF]

Neuropsychopharmacol Rep
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Goshima Y, Nakamura H, Koga M, Koyama J, Kimura Y, Vasishth MN, Snyder EY, Asai M, Sakai K, Masukawa D.   +9 more
europepmc   +2 more sources

The aromatic amino acid hydroxylase genes AAH1 and AAH2 in Toxoplasma gondii contribute to transmission in the cat [PDF]

, 2017
The Toxoplasma gondii genome contains two aromatic amino acid hydroxylase genes, AAH1 and AAH2 encode proteins that produce L-DOPA, which can serve as a precursor of catecholamine neurotransmitters.
Dubey, Jitender P, Sibley, L. David, Verma, Shiv K, Wang, Zi T   +3 more
core   +6 more sources

Biomedical and Clinical Importance of Mussel-Inspired Polymers and Materials

Marine Drugs, 2015
The substance secreted by mussels, also known as nature’s glue, is a type of liquid protein that hardens rapidly into a solid water-resistant adhesive material.
Nagendra Kumar Kaushik, Neha Kaushik, Sunil Pardeshi, Jai Gopal Sharma, Seung Hyun Lee, Eun Ha Choi   +5 more
doaj   +1 more source

Genetic associations of single nucleotide polymorphisms in the l-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice

Journal of Pharmacological Sciences, 2020
l-3,4-dihydroxyphenylalanine (l-DOPA) is a candidate neurotransmitter. l-DOPA is released by nicotine through nicotinic receptors. Recently, G-protein coupled receptor GPR143, was identified as a receptor for l-DOPA.
Daiki Masukawa, Daisuke Nishizawa, Kaori Kanai, Satoshi Kitamura, Yuka Kasahara, Tatsuo Hashimoto, Ryo Takahagi, Junko Hasegawa, Kyoko Nakayama, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda, Yoshio Goshima   +13 more
doaj   +1 more source

Early diagnosis of focal congenital hyperinsulinism: A fluorine-18-labeled l-dihydroxyphenylalanine positron emission tomography/computed tomography study

World Journal of Nuclear Medicine, 2021
Congenital hyperinsulinism (CHI) is responsible for hyperinsulinemic hypoglycemia which needs aggressive treatment in order to prevent neurological damages.
Luca Burroni, Andrea Palucci, Giuseppina Biscontini, Valentino Cherubini   +3 more
doaj   +1 more source

Obstruction of Water Uptake in cut Chrysanthemum Stems after Dry Storage: Role of Wound-induced Increase in Enzyme Activities and Air Emboli [PDF]

, 2009
Hydraulic conductance of cut chrysanthemum stems was lowered by the aspiration of air as well as by a wound-induced plant response. By measuring the hydraulic conductance of stem segments in which air could be introduced into and/or removed from the ...
Arevalo-Galarza, L., Meeteren, U., van
core   +2 more sources

Efficient production of salvianic acid A from l-dihydroxyphenylalanine through a tri-enzyme cascade

Bioresources and Bioprocessing, 2023
Salvianic acid A (SAA), used for treating cardiovascular and cerebrovascular diseases, possesses several pharmacological properties. However, the current methods for the enzymatic synthesis of SAA show low efficiency.
Jiahui Yang, Wanqing Wei, Changzheng Gao, Wei Song, Cong Gao, Xiulai Chen, Jia Liu, Liang Guo, Liming Liu, Jing Wu   +9 more
doaj   +1 more source

Synthesis of tripodal catecholates and their immobilization on zinc oxide nanoparticles [PDF]

, 2015
A common approach to generate tailored materials and nanoparticles (NPs) is the formation of molecular monolayers by chemisorption of bifunctional anchor molecules. This approach depends critically on the choice of a suitable anchor group.
Gross, Silvia, Hensel, Andreas, Klitsche, Franziska, Maison, Wolfgang, Migenda, Julia, Ramcke, Julian, Vossmeyer, Tobias, Weller, Horst   +7 more
core   +3 more sources