Results 71 to 80 of about 261 (135)

Exploring the Diverse Landscape of Fungal Cytochrome P450‐Catalyzed Regio‐ and Stereoselective Dimerization of Diketopiperazines

Advanced Science
Dimeric indole‐containing diketopiperazines (di‐DKPs) are a diverse group of natural products produced through cytochrome P450‐catalyzed C–C or C–N coupling reactions.
Chuanteng Ma, Wenxue Wang, Kaijin Zhang, Falei Zhang, Yimin Chang, Chunxiao Sun, Qian Che, Tianjiao Zhu, Guojian Zhang, Dehai Li   +9 more
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A NOVEL CLASS OF DIKETOPIPERAZINES

The Journal of Antibiotics, 1973
R L, DeVault, W, Rosenbrook
openaire   +3 more sources

Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors

Communications Chemistry
Chemotherapy-induced drug resistance remains a major cause of cancer recurrence and patient mortality. ATP binding cassette subfamily B member 1 (ABCB1) transporter overexpression in tumors contributes to resistance, yet current ABCB1 inhibitors have ...
Javier Yu Peng Koh, Yoko Itahana, Alexander Krah, Habib Mostafa, Mingmin Ong, Sahana Iwamura, Dona Mariya Vincent, Sabhashina Radha Krishnan, Weiying Ye, Pierre Wing Chi Yim, Tushar M. Khopade, Kunihiko Chen, Pui San Kong, Lin-Fa Wang, Roderick W. Bates, Yasuhisa Kimura, Rajesh Viswanathan, Peter J. Bond, Koji Itahana   +18 more
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TRANSFORMATIONS OF AN ACYL DIKETOPIPERAZINE

Journal of Biological Chemistry, 1944
Max Bergmann, Josephine E. Tietzman
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Oxidation of Tyrosine Diketopiperazine to DOPA Diketopiperazine with Tyrosine Hydroxylase

Journal of Natural Products, 2004
The diketopiperazine of DOPA was synthesized in high yield from the diketopiperazine of tyrosine using PC12 cell lysate, which expresses high levels of tyrosine hydroxylase. This represents the first use of this enzyme to prepare DOPA-containing peptides.
Maysoon B, Saleh, Russell G, Kerr
openaire   +2 more sources

2,5-Diketopiperazines as Neuroprotective Agents

Mini-Reviews in Medicinal Chemistry, 2012
2,5-diketopiperazines are the simplest cyclic peptides found in nature, commonly biosynthesized from amino acids by different organisms, and represent a promising class of biologically active natural products. Their peculiar heterocyclic structure confers high stability against the proteolysis and constitutes a structural requirement for the active ...
CORNACCHIA, CATIA, CACCIATORE, Ivana, BALDASSARRE, LEONARDO, MOLLICA, ADRIANO, FELICIANI, FEDERICA, PINNEN, Francesco Enrico   +5 more
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Diketopiperazines in wines

Journal of Wine Research, 2018
ABSTRACTThis study describes the identification of cyclic dipeptides known as diketopiperazines in red, white and sparkling wines from Greek market. Diketopiperazines have been isolated from bottled wines after liquid–liquid extraction and identified using gas chromatography coupled with mass spectrometry.
Eygenia Stamatelopoulou, Sofia Agriopoulou, Euthalia Dourtoglou, Arhontoula Chatzilazarou, Fotini Drosou, Marina Marinea, Vassilis Dourtoglou   +6 more
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Improvements in Aldol Reactions with Diketopiperazines.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Juan Francisco González, Elena de la Cuesta, Carmen Avendaño   +2 more
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Diketopiperazines from Marine Organisms

Chemistry & Biodiversity, 2010
AbstractDiketopiperazines (DKPs), which are cyclic dipeptides, have been detected in a variety of natural resources. Recently, the interest in these compounds increased significantly because of their remarkable bioactivity. This review deals with the chemical structures, biosynthetic pathways, and biological activities of DKPs from marine ...
Riming, Huang, Xuefeng, Zhou, Tunhai, Xu, Xianwen, Yang, Yonghong, Liu   +4 more
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Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria

Journal of Fermentation and Bioengineering, 1997
Abstract Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly- l -Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously ...
Hiroshi Kanzaki, Shuji Oda, Akio Kobayashi, Kazuyoshi Kawazu   +3 more
openaire   +1 more source