Results 71 to 80 of about 3,824 (213)

Catalytic Asymmetric Synthesis of Diketopiperazines by Intramolecular Tsuji–Trost Allylation

open access: yes, 2019
We report the intramolecular Tsuji–Trost reaction of Ugi adducts to give spiro-diketopiperazines in high yield and with high enantioselectivity. This approach allows the catalytic asymmetric construction of a broad range of these medicinally important ...
Matteo Faltracco (7364618)   +3 more
core   +2 more sources

Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine‐Derived Fungus Aspergillus flavus

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Two new asperfurans (1 and 2) and 23 known compounds from marine Aspergillus flavus were characterized by NMR, HRESIMS, DP4+, and ECD. Asperfuran (3) potently inhibited RSL3‐induced ferroptosis (EC50 = 0.81 µM). ABSTRACT Marine microorganisms represent a prolific reservoir of chemically diverse natural products endowed with considerable therapeutic ...
Chun‐Xiu Wang   +4 more
wiley   +1 more source

Asymmetric Synthesis of α-Trifluoromethyl Substituted Aminoacids via 3-Hydroxy-3-trifluoromethyl-2,5-diketopiperazines

open access: yes, 1994
Seymour LC, Burger K, Osipov SN, Kolomiets AV, Fokin AF, Sewald N. Asymmetric Synthesis of &#945-Trifluoromethyl Substituted Aminoacids via 3-Hydroxy-3-trifluoromethyl-2,5-diketopiperazines. Tetrahedron: Asymmetry.
Seymour, Liza C.   +11 more
core   +1 more source

Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive

open access: yesEFSA Journal, Volume 24, Issue 9, September 2026.
Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF)   +34 more
wiley   +1 more source

Synthesis of alkaloids based on tryptophan with structures of pyrrolidinoindolines diketopiperazines

open access: yes, 2021
Síntesis de dicetopiperazinas heterodiméricas y de octahidronaftalenos por reacción de Diels-Alder IntramolecularSíntese de dicetopiperazinas heterodiméricas e de octahidronaftalenos por reacción de Diels-Alder IntramolecularSynthesis of heterodimeric ...
Areal Gonzalez, Andrea
core  

Microbial diversity of saline environments: searching for cytotoxic activities

open access: yesAMB Express, 2017
In order to select halophilic microorganisms as a source of compounds with cytotoxic activities, a total of 135 bacterial strains were isolated from water and sediment samples collected from the Zipaquirá salt mine in the Colombian Andes.
Carolina Díaz-Cárdenas   +8 more
doaj   +1 more source

Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga   +5 more
wiley   +1 more source

Diverse Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces cejpii F31-1

open access: yesMarine Drugs, 2017
By adding l-tryptophan and l-phenylalanine to GPY medium, twenty-eight compounds, including amides, polyketides, a sesquiterpenoid, a diterpenoid, a meroterpenoid, diketopiperazines, β-carbolines, fumiquinazolines, and indole alkaloids, were discovered ...
Yan-Xiu Chen   +8 more
doaj   +1 more source

Diketopiperazines from Marine Actinomycetes

open access: yes, 2007
Diketopiperazines (DKPs) are a class of cyclic compounds that result from peptide bonds between two amino acids to form a lactam and are widespread as metabolites of various bacteria and fungi.
이정수   +4 more
core  

New Angucyclines and Antimicrobial Diketopiperazines from the Marine Mollusk-Derived Actinomycete An 113

open access: yesNatural Product Communications, 2010
Two new angucyclines, saccharothrixmicines A ( 2 ) and B ( 3 ), together with three known diketopiperazines 4-6 were isolated from the actinomycete Saccharothrix espanaensis An 113 associated with the marine mollusk Anadara broughtoni.
Nataliya I. Kalinovskaya   +4 more
doaj   +1 more source

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